Coronary Artery Disease in a Young USAF Pilot: Screening for Premature Artherosclerosis

Blair, Richard E.

doi:10.7205/milmed-d-09-00147

Cited by 2 publications

(1 citation statement)

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“…Our findings are rationale and valuable since CAD was effectively documented in a group of aviators who were over 40 years old and did not suffered any cardiovascular events. Blair et al (11) reported a case of young 38 years old military pilot with acute coronary syndrome developed after an 8 hour-flight and issued that TT followed by MSCT, in lieu of coronary angiography, was highly sensitive and specific in the diagnosis of CAD. In a review of cardiac events among USAF aviators during years 1988-92 it was reported that myocardial infarction occurred in 23 aviators, angina in 7 and sudden death in 8 aviators with an average of 7.6 events per year.…”

Section: Discussionmentioning

confidence: 99%

Clinical features of aviators with coronary artery disease diagnosed by multislice CT angiography

Erdal¹,

Aparcı²,

Işılak³

et al. 2014

Anadolu Kardiyol Derg

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Objective: Coronary artery disease (CAD) is one of the most incapacitating causes at military or civilian aviation. Aircrew population is crowding in number in our country. We aimed to identify the clinical features that could predict CAD in aircrew. Methods: We retrospectively analyzed medical recordings of 26 aircrew (age 43.57±5.2) whose CAD was diagnosed via multislice computerized tomography angiography (MSCT). Clinical features, coronary risk factors and ST segment and T wave changes on resting ECG and treadmill test (TT), and laboratory findings of aircrew were recorded. Results: ST depression <0.05 mV and minimally inversion (<0.03 mV) of T wave were found on 53.8% and 23.1% of resting ECG, respectively. 53.8% of patients had the family history of CAD. 73.1% of subjects were overweight. Family history was correlated with CAD and its type (p=0.023). 76.9% and 23.1% of the subjects had equivocal and positive result on TT, respectively. Presence of hypertension, hyperlipidemia, and smoking were lower and diabetes was absent. Additionally, subjects with two or more vessel disease were observed slightly older compared to those with one vessel disease (45.5±3.8 vs. 42.2±5.5, p=0.101). Conclusion: Aircrew ≥40 years old, with family history, ST/T changes on resting ECG, and equivocal results on TT even in the absence of multiple coronary risk factors may need further cardiovascular tests. MSCT is an effective and noninvasive way of detection of CAD in aircrew when needed. (Anadolu Kardiyol Derg 2014; 14: 150-4)

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Section: Discussionmentioning

confidence: 99%

Clinical features of aviators with coronary artery disease diagnosed by multislice CT angiography

Erdal¹,

Aparcı²,

Işılak³

et al. 2014

Anadolu Kardiyol Derg

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Coronary Heart Disease in Young Adults

Rubin

Borden

2012

Curr Atheroscler Rep

110

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Despite the recent decline in mortality from coronary heart disease (CHD), this disease remains the leading killer of US adults of all ages. CHD in young adults is not as well characterized as CHD in older individuals because it occurs less frequently, but this disease can have devastating consequences for young patients and their families. As in older adults, the majority of coronary events in young adults are related to atherosclerosis, and one or more of the traditional CHD risk factors is typically present. Young patients, however, are more likely than older patients to be smokers, male, obese, and to have a positive family history. Risk factor reduction is thus of major importance in managing young CHD patients. Approximately 20% of CHD in young adults, however, is related to non-atherosclerotic factors, such as coronary abnormalities, connective tissue disorders, and autoimmune diseases. Cocaine and other illicit drug use have been increasingly associated with acute myocardial infarction and accelerated atherosclerosis. The differences in etiologies and risk profiles of younger and older CHD patients result in differences in disease progression, prognosis, and treatment. Limited data suggest that prognosis may be better in the young population, although long-term mortality studies have suggested otherwise. Screening for CHD in the young population may help to improve prognosis in young patients by detecting subclinical disease, although more studies are necessary to establish reference limits for this young population. Additional research must also focus on treatment concerns that are specific to young patients.

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Coronary Artery Disease in a Young USAF Pilot: Screening for Premature Artherosclerosis

Cited by 2 publications

References 0 publications

Clinical features of aviators with coronary artery disease diagnosed by multislice CT angiography

Clinical features of aviators with coronary artery disease diagnosed by multislice CT angiography

Coronary Heart Disease in Young Adults

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