Coronary Artery Disease in South Asians

Bedi, Updesh; Singh, Sarabjeet; Syed, Asmir I.; Aryafar, Hamed; Arora, Rohit

doi:10.1097/01.crd.0000182411.88146.72

Cited by 38 publications

(37 citation statements)

References 59 publications

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“…The prevalence of diabetes, hypertension and low HDL in this population is consistent with previously reported data [3,43,44]. However, the literature has shown that traditional risk factors for CAD may not fully explain the excessive CAD risk in South Asians as compared to Caucasians, and the search for other markers is required, especially for this population [6,45].…”

Section: Discussionsupporting

confidence: 89%

“…We could not find an association of other CAD risk factors with pro-inflammatory HDL, and there is no plausible explanation except the small sample size. Similarly, several studies have shown Lpa to be a risk factor for CAD as well as carotid IMT [43,44]. We could not find this association in our study, however Lpa was associated with dysfunctional HDL measured by HDL inflammatory Index (Table 4).…”

Section: Discussioncontrasting

confidence: 51%

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Can dysfunctional HDL explain high coronary artery disease risk in South Asians?

Dodani

Kaur

Reddy

et al. 2008

International Journal of Cardiology

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Section: Discussionsupporting

confidence: 89%

Section: Discussioncontrasting

confidence: 51%

Can dysfunctional HDL explain high coronary artery disease risk in South Asians?

Dodani

Kaur

Reddy

et al. 2008

International Journal of Cardiology

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“…Migrant populations carry along disease characteristics, inherited from their place of origin, 11 which affect future risk of CVD. The CVD risk profile among migrant populations, however, may change over time as they get exposed to the factors of their host environment.…”

Section: Boateng Et Al Cardiovascular Disease Risk Among Ghanaian Migmentioning

confidence: 99%

Migration and Cardiovascular Disease Risk Among Ghanaian Populations in Europe:

Boateng

Agyemang²,

Beune³

et al. 2017

Circ: Cardiovascular Quality and Outcomes

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M igrants' health is an important public health issue 1 with growing evidence supporting the role of migration in the development of noncommunicable diseases. [2][3][4] Migrant populations from sub-Saharan Africa (SSA) seem to be affected disproportionately by cardiovascular diseases (CVDs) and related risk factors, including hypertension, obesity, and diabetes mellitus. 5,6 For instance, the prevalence of hypertension in The Netherlands relative to Dutch people is higher in all ethnic minority groups, with the exception of Moroccan women. 7 Evidence from Canada, however, shows better CVD risk profile among migrants than the host population. 8 This shows the importance of diverse factors (including acculturative stress resulting from the feeling of isolation, discrimination, alienation and dislocation, Background-For migrant populations from sub-Saharan Africa, adverse cardiovascular disease (CVD) risk factors have been observed to be higher than found in their home country-based counterparts or among the host populations in high-income countries. Differences in absolute overall CVD risk, however, remain largely unexplained. We, therefore, predicted the differences in 10-year CVD risk among sub-Saharan African migrants (Ghanaians) living in 3 European cities and Ghana. Methods and Results-For 3864 subjects aged 40 to 70 years from the multicenter RODAM study (Research on Obesity and Diabetes Among African Migrants) conducted among Ghanaian adults residing in rural and urban Ghana and 3 European cities (Amsterdam, Berlin, and London), 10-year risk of CVD was estimated using the Pooled Cohort Equations with estimates ≥7.5% defining high CVD risk. Logistic regressions were used to determine the association of migration on CVD risk. Migrant populations carry along disease characteristics, inherited from their place of origin, 11 which affect future risk of CVD. The CVD risk profile among migrant populations, however, may change over time as they get exposed to the factors of their host environment. 12 This results in differences in CVD risk between similar populations residing in different industrialized countries. For instance, Agyemang et al 13 found that people of African descent residing in England had a lower prevalence of type 2 diabetes mellitus than those residing in The Netherlands, and these differences reflected the difference in prevalence of CVDs of their host countries. 14The reasons for these differences are unclear but could include cross-national differences in health behaviors and related factors, such as socioeconomic position, accessibility, and utilization of preventive services. 13,15 CVDs reflect the combined effect of several risk factors, 16 which tend to appear in clusters.17 Current guidelines for CVD risk reduction have, therefore, reiterated the need to assess all risk factors as a more effective basis to deliver CVD prevention interventions.16 Absolute CVD risk estimates, using established risk algorithms, help to determine the probability of a cardiovascular event occurring within a sp...

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“…South Asian knowledge of and attitudes to health risks a uK National Health service survey found that many sas are unaware of their increased risk of CVD and T2D. Even when they have developed disease, sas are often not aware of related causes and complications or preventive measures, such as healthier foods or cooking methods, despite public health campaigns and publicity 14,50,51 . an additional problem is that sas are reluctant to accept that amelioration of their condition is within their control.…”

Section: South Asians and Key Cvd Risk Factorsmentioning

confidence: 99%

South Asians and their increased cardiovascular risk: A review of risk factors and diet and lifestyle modification

Nicoll¹,

Henein²

2015

ICFJ

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South Asians (SAs) have a significantly higher incidence and severity of type 2 diabetes and cardiovascular disease (CVD) than Caucasians and can present with atypical ischaemic symptoms. This can present a challenge for health professionals who may not be aware of the lowered thresholds recommended for SA body mass index, waist circumference and age. Although SAs are likely to have all the hallmarks of metabolic syndrome: central obesity, insulin resistance, impaired glucose tolerance, reduced high density lipoprotein, high triglycerides and hypertension, conventional risk factors alone do not fully predict the increased CVD risk among this community. Furthermore, SAs themselves may not be aware of their increased predisposition to disease nor of the dietary and lifestyle modifications which could reduce the risk and severity of their condition. Even where some modification has been attempted, there may be cultural pressure to conform to a traditional diet and the requirements for fasting and feasting. Principally, SAs should avoid large late meals, reduce sugary sweets and drinks, alcohol and foods fried in plant oils which create damaging transfats, while increasing protein and non-fried vegetables to help glycaemic control. Chewing paan, with or without added tobacco, is a particular risk factor for both CVD and cancer, on a par with the dangers of smoking. Although not in the culture, exercise would also be of great benefit.

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Coronary Artery Disease in South Asians

Cited by 38 publications

References 59 publications

Can dysfunctional HDL explain high coronary artery disease risk in South Asians?

Can dysfunctional HDL explain high coronary artery disease risk in South Asians?

Migration and Cardiovascular Disease Risk Among Ghanaian Populations in Europe:

South Asians and their increased cardiovascular risk: A review of risk factors and diet and lifestyle modification

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