Coronary artery myointimal dysplasia in patients with pheochromocytoma—possible causal relationship: pathophysiology and clinical implication with reference to Takotsubo cardiomyopathy and spontaneous coronary dissection

Chow, Louis T. C.; Chow, Maria Bernadette Che Ying

doi:10.1016/j.carpath.2018.10.001

Cited by 4 publications

(2 citation statements)

References 58 publications

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“…Catecholamine surges have been previously implicated in the pathophysiology of SCAD. In fact, Chow et al proposed that surges in catecholamines lead to vascular myointimal dysplasia and this may underlie the association observed between emotional stress and SCAD [ 8 ]. Additionally, estradiol levels are also often blunted in AN, and estradiol is protective of the vascular endothelium in several animal models [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

A Case of Spontaneous Coronary Artery Dissection in a Patient with Severe Anorexia Nervosa

O'Neil

Mazumder

Sanborn

et al. 2021

Case Reports in Cardiology

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There are a variety of cardiac complications of anorexia nervosa including arrythmias, valvopathies, and myopathies. Spontaneous coronary artery dissection (SCAD) has not been widely reported among this patient population. This case report describes a middle-aged female with severe anorexia nervosa, who presented after being found unconscious, and was later diagnosed with SCAD. A literature review revealed one previous case of SCAD in a patient with anorexia nervosa and prompted a discussion of a series of possible predisposing factors for SCAD in this patient population. Patients with anorexia nervosa may be at increased risk for SCAD due to their complex nutritional and endocrine imbalances. This case highlights a possible underdiagnosed cardiac complication of anorexia nervosa.

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Section: Discussionmentioning

confidence: 99%

A Case of Spontaneous Coronary Artery Dissection in a Patient with Severe Anorexia Nervosa

O'Neil

Mazumder

Sanborn

et al. 2021

Case Reports in Cardiology

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show abstract

“…The patient commonly presents with chest pain, dyspnea, palpitation, nausea and vomiting, syncope as well as cardiogenic shock. However, Takotsubo cardiomyopathy usually occurs in association with a preceding physical or emotional stressful event (6,7). This is usually the case in more than 70% of the cardiomyopathies.…”

Section: Introductionmentioning

confidence: 99%

Takotsubo Cardiomyopathy: Broken Heart Syndrome in A Tertiary Teaching & Referral Hospital in East Africa: Case Report & Literature Review

William,

Chesoni,

Madekwe

et al. 2023

AJHMN

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Purpose: Takotsubo cardiomyopathy (TC), also known as broken heart syndrome, refers to an abrupt and short-lived cardiac syndrome that encompasses dramatic left ventricular apical akinesia. besides mirroring acute coronary syndrome. Patients with Takotsubo cardiomyopathy (broken heart syndrome) usually present with symptoms that are similar to acute coronary syndrome. The patient commonly presents with chest pain, dyspnea, palpitation, nausea and vomiting, syncope as well as cardiogenic shock. However, Takotsubo cardiomyopathy usually occurs in association with a preceding physical or emotional stressful event. Methodology: A 25-year-old black female presented to the largest teaching & referral hospital in Kenya with chest pain, dyspnea, palpitations, nausea and vomiting. The patient was received in the emergency room where she was stabilized, a battery of investigations ordered and a diagnosis of TC was made after reviewing the results. She was managed as an inpatient on appropriate medication Findings: Patient generally responded positively to the treatment and tolerated well the surgical procedures. Follow up echocardiograms performed weekly revealed progressive reduction in size of the thrombus, which had completely resolved at 4 weeks. There was no more thrombi formation after thromboembolectomy of the left femoral artery. Recommendations: TC is a rescindable type of cardiomyopathy that is associated with good prognosis and an exceptional morphological characteristic of the left ventricle, that is defined by apical inflating appearance that has been recognized for nearly a quarter a century. We also recommend that patients with identified LV thrombus ought to be anticoagulated till LV function normalizes in addition to the thrombus no longer being present on echocardiogram.

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Sex Differences Across the Lifespan: A Focus on Cardiometabolism

Kumar

Reusch

Kohrt

et al. 2020

Journal of Women's Health

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Coronary artery myointimal dysplasia in patients with pheochromocytoma—possible causal relationship: pathophysiology and clinical implication with reference to Takotsubo cardiomyopathy and spontaneous coronary dissection

Cited by 4 publications

References 58 publications

A Case of Spontaneous Coronary Artery Dissection in a Patient with Severe Anorexia Nervosa

A Case of Spontaneous Coronary Artery Dissection in a Patient with Severe Anorexia Nervosa

Takotsubo Cardiomyopathy: Broken Heart Syndrome in A Tertiary Teaching & Referral Hospital in East Africa: Case Report & Literature Review

Sex Differences Across the Lifespan: A Focus on Cardiometabolism

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