Coronary Atherosclerosis in Valvular Heart Disease

Lacy, Jerome P.; Goodin, Robert R.; McMartin, Daniel E.; Masden, Ronald; Flowers, Nancy C.

doi:10.1016/s0003-4975(10)64162-8

Cited by 43 publications

(9 citation statements)

References 6 publications

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“…In comparison to mitral valve disease, aortic valve disease and combined lesion have significantly higher chance of coronary artery disease (p=0.001). The findings are supported by Moraski RE et al [12] and Lacy J et al [13] CONCLUSION Overall prevalence of significant coronary artery disease in patients with valvular heart disease is 14.28% in this part of the country. Prevalence of coronary artery disease in rheumatic valvular heart disease is 9.26%, while in nonrheumatic valvular heart disease it is 44.44%.…”

Section: Discussionsupporting

confidence: 66%

Prevalence of Coronary Artery Disease in Patients With Valvular Heart Disease

Saharia¹,

Devi²

2016

jemds

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BACKGROUNDHeart disease is a growing problem, particularly in developing countries. India has quoted to have 12.2% and 12% prevalence of coronary artery disease and rheumatic valvular heart disease respectively. Some older reports suggest that rheumatic fever, i n addition to producing specific injuries to small coronary arterial branches may accelerate the development of coronary atherosclerosis.

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Section: Discussionsupporting

confidence: 66%

Prevalence of Coronary Artery Disease in Patients With Valvular Heart Disease

Saharia¹,

Devi²

2016

jemds

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“…In the study by Lacy et al, the patients were evaluated for the presence of concurrent CAD (50% or greater occlusion in at least one major coronary artery), they found that 31.3% of the patients with MS had CAD and 19% had occlusive CAD, and 36.3% of the patients with MR had CAD and 18% had occlusive CAD, and 58.9% of the patients with AS had CAD and 21% had occlusive CAD, and 36.6% of the patients with AR had CAD and 30% had occlusive CAD [30]. …”

Section: Discussionmentioning

confidence: 99%

Evaluation of the prevalence of coronary artery disease in patients with valvular heart disease

Emren

Kiliçaslan

et al. 2014

J Cardiothorac Surg

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ObjectivesThe aim of the present study was to retrospectively evaluate the prevalence of concurrent coronary artery disease in patients who underwent surgery due to severe valvular heart disease. The study also investigated the association of coronary artery disease with the type of valvular heart disease.Materials and methodsA total of 241 patients (123 females [51%]), who had underwent single valvular heart surgery, were included in the study. The patients who underwent valve replacement surgery were divided into four groups: patients with severe mitral stenosis (MS), patients with severe mitral regurgitation (MR), patients with severe aortic regurgitation (AR), and patients with severe aortic stenosis (AS). Age, DM, HT, history of smoking, and LDL values were recorded as the risk factors for CAD.ResultsCoronary artery disease was detected in 26.4% of patients with mitral stenosis and 57.7% of patients with aortic stenosis. Of the patients with mitral insufficiency, 41.9% had CAD, and 44.4% of the patients with aortic insufficiency had CAD.ConclusionThe comparison of MS and AS groups revealed significantly higher prevalence of CAD in the AS group. There was no statistically significant difference between the MR and AR groups in terms of the prevalence of CAD. The comparison of MS and MR groups revealed significantly higher prevalence of CAD in the MR group. Furthermore, the comparison of these groups in terms of the extensiveness of the coronary artery disease revealed significantly higher Gensini score in the MR group.

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“…The prevalence of CAD in patients with MS (an average of 20%) is lower than in patients with aortic valve disease, 1015,1017,1018,1021,1022 an observation explained principally on the basis of differences in age and gender. Nonetheless, because of the impact of untreated CAD on perioperative and long-term postoperative survival, preoperative identification of CAD is of great importance in patients with AR or MS and those with AS.…”

Section: Probability Of Coronary Artery Disease In Patients With Valvmentioning

confidence: 95%