Coronary computed tomography angiography versus invasive coronary angiography: medical staff perceptions and diagnostic interest in Gaza-Palestine

Mansour, Husam H; Alajerami, Y.S.M.; Najim, Ahmed

doi:10.1007/s11845-020-02376-3

Cited by 3 publications

(1 citation statement)

References 37 publications

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“…Due to its high temporal and spatial resolution, CCTA can provide the anatomical information of lesions, including the features, extent, and severity of stenosis. This method enjoys a reputation as an accurate noninvasive first-line method in the guidelines to evaluate patients with a low-to-intermediate risk of CAD due to its high sensitivity, specificity, and negative predictive value (21). However, its diagnostic accuracy may reduce because of respiratory artifacts and calcified plaques; besides, it cannot show whether coronary artery lesions have any hemodynamic significance (22).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the Advantages of Myocardial Blood Flow Index in the Diagnosis of Chronic Obstructive Coronary Artery Disease Versus Coronary Computed Tomography Angiography: A Feasibility Study

Qingfeng

et al. 2022

Iran J Radiol

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Background: There is a hidden relationship between the degree of coronary artery stenosis and downstream myocardial remodeling. The mutual influence in myocardial ischemia and myocardial remodeling provides an index for quantifying the myocardial blood flow based on the principles of physics. Objectives: This study aimed to evaluate the advantages of myocardial blood flow index (MBFI) in the diagnosis of chronic obstructive coronary artery disease (CAD). Patients and Methods: The data of 68 patients (39 males; mean age: 57.0 ± 10.20 years) with suspected CAD were analyzed retrospectively, including the imaging findings of coronary computed tomography angiography (CCTA) and invasive coronary angiography (ICA) within one week. The MBFI was also calculated for the patients. After determining the optimal cut-off value based on ICA (stenosis ≥ 70%) as the gold standard test, the diagnostic performance of MBFI and CCTA was compared. The diagnostic accuracy was examined by the receiver operating characteristic (ROC) curve. For statistical analysis, chi-square test was performed to analyze influence data, and a P-value less than 0.05 was considered statistically significant. Results: In 68 cases evaluated in this study, the average scan dose of CCTA was 3.02 ± 1.15 mSv. There were 28 cases with stenosis ≥ 70%. The optimal cutoff value of MBFI and CCTA was 0.111 and 70%, respectively. Also, the area under the curve (AUC) for MBFI and CCTA was 0.857 and 0.621 (Z = 2.091, P = 0.0365), respectively. The sensitivity, specificity, positive predictive value, and negative predictive value were 92.31%, 92.86%, 88.89%, and 95.12% for MBFI and 61.54%, 78.57%, 64.00%, and 76.74% for CCTA, respectively. The diagnostic accuracy was also estimated at 92.65% for MBFI and 72.06% for CCTA (χ2 = 9.844, P = 0.0017). Conclusion: In this study, MBFI performed better than CCTA in identifying lesions with stenosis ≥ 70%. A lower MBFI indicated the need for an upcoming active intervention, while a higher MBFI suggested avoiding unnecessary invasive testing.

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Section: Discussionmentioning

confidence: 99%

Evaluation of the Advantages of Myocardial Blood Flow Index in the Diagnosis of Chronic Obstructive Coronary Artery Disease Versus Coronary Computed Tomography Angiography: A Feasibility Study

Qingfeng

et al. 2022

Iran J Radiol

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The diagnostic accuracy of coronary computed tomography angiography in patients with and without previous coronary interventions

Mansour

Alajerami

Abushab

et al. 2022

Journal of Medical Imaging and Radiation Sciences

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Estimation of Radiation Doses and Lifetime Attributable Risk of Radiation-induced Cancer from A Single Coronary Artery Bypass Graft Computed Tomography Angiography

2021

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Despite worldwide consensus that coronary artery bypass graft computed tomography angiography (CABG CTA) confers benefit to patients when used for appropriate indications, the increased cancer risk due to radiation dose remains a concern. The aim of this study is the estimation of organ effective dose (ED) and lifetime attributable risk (LAR) of cancer incidence and mortality related to a single CABG CTA procedure. Methods and materials:This retrospective cross-sectional designed study included 102 CABG patients who, from January 2021 to June 2021, underwent a retrospective 64-slice ECG-gated CABG CTA covering the area of the grafts with optimal image quality. The estimation of ED was done using the imPACT CT Dosimetry spreadsheet. LAR of cancer incidence was estimated for CABG CTA using the website X-rayrisk.com. Results:The mean total ED of CABG procedure was 15.35 mSv. The highest organ doses were those to the lungs (5.04 mSv) and breast (4.49 mSv). The cancer risk is higher in female (1 in 1516) than in male patients (1 in 1762). The LAR of cancer is higher for the younger age group in both males and females. The total whole-body ED demonstrated that CABG CTA is equivalent to 154 chest radiographs or 37 screening mammography studies, which in turn correspond to approximately 4.3 or 5-years of natural background radiation, respectively.Conclusions: Despite many benefits of CABG CTA, it is associated with a non-negligible risk of malignancy, so a careful risk/benefit assessment is recommended in justifying CABG CTA procedures, especially for young female patients.

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Coronary computed tomography angiography versus invasive coronary angiography: medical staff perceptions and diagnostic interest in Gaza-Palestine

Cited by 3 publications

References 37 publications

Evaluation of the Advantages of Myocardial Blood Flow Index in the Diagnosis of Chronic Obstructive Coronary Artery Disease Versus Coronary Computed Tomography Angiography: A Feasibility Study

Evaluation of the Advantages of Myocardial Blood Flow Index in the Diagnosis of Chronic Obstructive Coronary Artery Disease Versus Coronary Computed Tomography Angiography: A Feasibility Study

The diagnostic accuracy of coronary computed tomography angiography in patients with and without previous coronary interventions

Estimation of Radiation Doses and Lifetime Attributable Risk of Radiation-induced Cancer from A Single Coronary Artery Bypass Graft Computed Tomography Angiography

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