Coronary flow obstruction in percutaneous aortic valve replacement. An in vitro study

Flécher, Erwan; Curry, John W.; Joudinaud, Thomas M.; Kegel, Corrine L.; Weber, Patricia A.; Durán, Carlos M.G.

doi:10.1016/j.ejcts.2007.04.033

Cited by 36 publications

(23 citation statements)

References 12 publications

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“…The recent advent of PAV, providing a non-operative treatment of symptomatic aortic valve disease, has necessitated continuing developments of devices, techniques, and treatment protocols for optimization of PAV procedures [14]. With the proximity of the coronary ostia to the aortic annulus and valve leaXets, a particularly challenging issue is the risk of obstruction of the coronary ostia during PAV replacement [2,4,9,11].…”

Section: Introductionmentioning

confidence: 99%

Ex vivo and in vivo coronary ostial locations in humans

et al. 2009

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Purpose Knowledge of the normal in vivo distribution and variation of coronary ostial locations is essential in the planning of various interventional and surgical procedures. However, all studies to date have reported the distribution of coronary ostia locations only in cadaver hearts. In this study, we sought to assess the distribution of coronary ostial locations in patients using cardiac dual-source computed tomography (CT) and compare these values to those of human cadaveric specimens. Methods Measurements of the coronary ostia location were performed in 150 patients undergoing dual-source CT and in 75 cadavers using open measurement techniques. All 150 patients had a normal aortic valve function and no previous cardiac intervention or surgery. The location of the right and left coronary origin in relation to the aortic annulus and the height of the sinus of Valsalva were measured. Conclusions This study provides data of normal coronary ostial origins and demonstrates signiWcant diVerences between in vivo and ex vivo measurements regarding the right coronary ostium. The observed large variations of coronary ostia origins emphasize the importance of considering such anatomic variations in the development of treatments. Results

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Section: Introductionmentioning

confidence: 99%

Ex vivo and in vivo coronary ostial locations in humans

et al. 2009

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“…In conclusion, the present study of Flecher et al [1] demonstrates that percutaneous valve technology requires significant benchmark research. We have to convince the sceptical physicians with solid scientific data.…”

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confidence: 83%

“…First, we would like to congratulate Flecher et al [1] for their work-an important contribution to basic research on percutaneous aortic valve technologies. Unfortunately, interest on basic research in this field seems to have decreased since the human clinical trials began.…”

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confidence: 99%