“…Furthermore, CAD progression documented after the second CCA suggests CV as an early manifestation of coronary allograft vasculopathy. 3 The hypothesis of pathological vasoreactivity in the donor's heart, compounded by factors like antibody-mediated rejection, is intriguing, yet purely speculative. On the other hand, DSAs normalization without symptom relief underscores the multifactorial nature of this phenomenon.…”