Coronavirus Disease 2019 (COVID-19) and pregnancy: what obstetricians need to know

Abstract

Word Count: 497 27 28 2

One size does not fit all – Patterns of vulnerability and resilience in the COVID-19 pandemic and why heterogeneity of disease matters

“…Interestingly, and in line with the pattern of COVID-19 producing milder symptoms in children, there is currently no evidence for increased risk of severe outcomes of COVID-19 in pregnant women. We should note, though, that this evidence is based on limited data, while reports from SARS-CoV, MERS-CoV and from other respiratory infections suggest these conclusions are premature and pregnant women could be at risk of a severe course of COVID-19 (Rasmussen et al, 2020). If, however, pregnancy proves to provide some protection from disease severity, it could offer unique opportunities for the development of therapeutic solutions.…”

Managing Asthma during Coronavirus Disease-2019: An Example for Other Chronic Conditions in Children and Adolescents

“…Since there is substantial overlap between the clinical presentation of worsening asthma and COVID-19 and increasing community spread lessens likelihood of known contact with a case, screening for COVID-19 is required if available in any asthmatic child who comes to medical attention with worsening cough or shortness of breath. (8,13)…”

“…(10,11) It is further reassuring that children appear to be at lower risk of COVID-19 morbidity and mortality than the adult population in general, although severe infection still can occur. (13,20) The CDC morbidity and mortality report notes that among the 149,082 reported U.S. cases of COVID-19 for which age is known, only 2572 (1.7%) occurred in In summary, based on available information to date, it is unclear whether there is a significantly increased risk of COVID-19 morbidity among asthmatic children. (8,9) It is also unknown whether asthma medications such as high-dose inhaled corticosteroids or asthma biological therapies pose a risk in managing COVID-19 infections.…”

A Controversial Debate: Vertical Transmission of COVID-19 in Pregnancy

“…Previous studies demonstrated that SARS infection during pregnancy is associated with adverse maternal and neonatal complications including spontaneous miscarriage, preterm delivery, intrauterine growth restriction, undergoing endotracheal intubation, admission to the intensive care unit, renal failure, and disseminated intravascular coagulopathy (8).…”