2020
DOI: 10.1016/j.hrtlng.2020.06.003
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Coronavirus disease 2019 (Covid-19) presenting as purulent fulminant myopericarditis and cardiac tamponade: A case report and literature review

Abstract: The vast majority of patients in the ongoing coronavirus Disease 2019 (Covid-19) pandemic primarily present with severe respiratory illness. We report a Covid-19 patient who presented with findings of acute coronary syndrome and was found to have purulent fulminant myopericarditis and cardiac tamponade. We compare our case to the previously reported instances of Covid-19-associated myocarditis. Through review of the available literature, we also highlight the potential mechanisms of cardiac injury in Covid-19.… Show more

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Cited by 29 publications
(50 citation statements)
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“…Usually, cardiovascular involvement in COVID-19 patients has been described as myocardial injury identified by troponin increase [11][12][13][14], thus a precise morphological and functional characterization of the heart in COVID-19 patients with clinically suspected myocarditis is lacking on a large scale. Nearly all the information about myocarditis in these patients comes from case reports or small series [15][16][17][18][19][20][21], which have been included in 3 systematic reviews so far [15][16][17].…”
Section: Prevalence Characteristics and Prognosis Of Myocarditis Inmentioning
confidence: 99%
“…Usually, cardiovascular involvement in COVID-19 patients has been described as myocardial injury identified by troponin increase [11][12][13][14], thus a precise morphological and functional characterization of the heart in COVID-19 patients with clinically suspected myocarditis is lacking on a large scale. Nearly all the information about myocarditis in these patients comes from case reports or small series [15][16][17][18][19][20][21], which have been included in 3 systematic reviews so far [15][16][17].…”
Section: Prevalence Characteristics and Prognosis Of Myocarditis Inmentioning
confidence: 99%
“…COVID-19 has been associated with myopericarditis in case studies, 1 , 2 , 3 , 4 and myocardial injury has been associated with increased morbidity and mortality. 5 , 6 Large studies using biopsy, histologic examination, and molecular-based testing for the severe acute respiratory syndrome coronavirus 2 genome in cardiac tissue are needed to illuminate the potential role of COVID-19 in myopericarditis.…”
Section: Diagnosismentioning
confidence: 97%
“…In the rest of the cases, the most reported laboratory blood tests included different combinations of troponin T, Troponin I, N-terminal pro b-type natriuretic peptide (NT-proBNP), and C-Reactive Protein (CRP), all of which, when done, were consistently elevated. Some cases also reported CK-MB levels as high [11,14,23,30,35]. One case reported an elevated serum myoglobin level [17].…”
Section: B) Laboratory Blood Testsmentioning
confidence: 99%
“…Other patients' ECGs showed non-specific ischemic changes such as T-wave inversions [11,26]. Tachyarrhythmias, mainly sinus tachycardia, was noted [17,18,25,28,30,34], as well as ventricular tachycardia and atrial fibrillation [2,19].…”
Section: Diagnostic Testing A) Ecg Findingsmentioning
confidence: 99%