Coronavirus Disease: A Review of a New Threat to Public Health

Abstract

In December 2019, several patients from Wuhan, China were admitted to hospitals with symptoms of pneumonia. As the number of patients presenting with similar symptoms started to rise, the causative agent was eventually isolated from samples. It was initially called the 2019 novel coronavirus (2019-nCoV) and has been recently relabelled as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2);

In-silico approaches to detect inhibitors of the human severe acute respiratory syndrome coronavirus envelope protein ion channel

“…Later, the World Health Organization (WHO) renamed that virus as 'severe acute respiratory syndrome coronavirus 2' (SARS-CoV2) and the diseased caused by them is known as 'coronavirus disease 2019' . On March 11, 2020, the WHO officially declared the outbreak of COVID-19 as a pandemic (Ramphul & Mejias, 2020). On March 28, 2020, 614169 confirmed cases with 28239 deaths and 933 confirmed cases are reported in India with 20 deaths (https://mohfw.gov.in & WHO).…”

“…The SARS-CoV2 is an enveloped virus that belongs to the Coronaviridae family (Ramphul & Mejias, 2020). CoVs assemble together nearby intracellular membranes within the Endoplasmic reticulum-Golgi intermediate compartment (or ERGIC) after infection.…”

Diagnostic methods and potential portable biosensors for coronavirus disease 2019

“…It is predicted that the SARS-CoV-2 has 28 proteins (Wu et al, 2020). The particle size of the whole virus ranges from 50 to 200 nm (Kim et al, 2020a;Ramphul and Mejias, 2020). According to previous reports, the M and E proteins are necessary for virus assembly (Neuman et al, 2011;Nieto-Torres et al, 2014).…”

Balancing Personal Privacy and Public Safety During COVID-19: The Case of South Korea

“…Hundreds of the church's leaders attended their international missionary outreach gathering in Wuhan, China and returned to Korea in January 2020. In the meantime, the number of confirmed patients increased explosively-up to 7,513 on March 10, 2020 [41,42,43].…”