Coronaviruses Pathogens in Human in Third Millennium (SARS-CoV, MERS, COVID-19): A Review Article

Abstract

This study aimed to investigate the most common Coronavirus pathogens in humans in the third millennium. In this study, all documents in English on pathogenic coronaviruses were examined from the beginning of 2002 to March 27, 2020. Articles were searched through reliable databases such as PubMed, Web of Science, Scopus, Google scholar, Science Direct, Cochrane library, and BioRxiv using the keywords "COVID-19", "Coronavirus 2019", "SARS-CoV," and" MERS-CoV." In addition, reliable health websites, such as WHO and the Centers for Disease Control and Prevention (CDC), were used to obtain new figures and information on these diseases. A total of 1563 articles and documents were extracted, and after reviewing the full texts of these articles, 100 papers and documents with necessary eligibility were finally selected in the present review study. The outbreak of pathogenic viruses, especially the latest one, i.e., COVID-19, as a severe threat can affect the entire global community, in particular medical staff who are at the forefront of fighting against the virus. It can generally be concluded that coronaviruses have high pathogenesis, with very rapid person-to-person transmission. Since human knowledge is not yet complete about the new type of this virus, i.e., COVID-19, there are no definitive treatments for the virus. Thus, the best and only way to prevent affection from this virus is currently fully implementing health protocols and preventing self-infection and the virus outbreak.