Corpus callosum and epilepsies

Abstract

CC is part of cerebral white matter and anomalies cannot act per se as seizure onset zone. Imaging techniques demonstrate additional lesions in patients with epilepsies. CC is the major pathway for seizure generalization. Therefore, callosotomy is used to prevent generalized drop seizures.

Heterogenous migraine aura symptoms correlate with visual cortex functional magnetic resonance imaging responses

“…30 Bilateral regional cerebral blood flow changes have been reported in single subjects using SPECT. 38 Another possible mechanism may be connectional diaschisis as described after stroke, where unilateral cortical lesions may lead to contralateral reduction of evoked potential, fMRI activation, 39 and regional cerebral blood flow. The other patients experienced bilateral visual symptoms, and we here show corresponding bihemispherical changes in BOLD response.…”

Brain Lesions in Children with Unilateral Spastic Cerebral Palsy

“…ACC is not indicative for seizure disorder, more often additional malformations of cortical development are causal. Microstructural CC abnormalities are detected by advanced imaging techniques and they constitute a part of diffuse white matter disturbance (12)(13)(14). In our study, there were 3 patients with ACC, two of them had epilepsy and all three of them were intellectually disabled.…”

Complete prefrontal lobe isolation surgery for recurrent epilepsy: A case report

“…These procedures disrupt the fiber connections between cortical columns, but not the projection fibers from the cortex to the subcortical centers (18). However, they are considered palliative as they may reduce seizure frequency or severity, but do not stop seizure activity (19). A previous study observed that hemispheric and posterior quadrantic disconnection achieved the same rates of seizure control as epileptogenic focus resection in patients with intractable epilepsy (20).…”