Corpus luteum hemorrhage in a patient with aplastic anemia

Abstract

Corpus luteum hemorrhage may lead to a life-threatening intraperitoneal hemorrhage in women with bleeding disorders. A 17-year-old girl with aplastic anemia presented to the emergency ward with complaints of severe abdominal pain for the last 24h. On examination, she was noted to be pale with circulatory compromise. Transabdominal pelvic ultrasonography revealed a left complex adnexal mass, 6.9×5.1×5.1cm(3) in size, with a large anechoic area of fluid in the abdomen. On laparoscopic exploration, there was a massive hemoperitoneum (2.6L) with a ruptured corpus luteum on the surface of the left ovary. Hemostatic electric coagulation was successfully applied to the bleeding surface. The patient recovered without incident and was transferred to a special hospital for blood disease treatment one week after surgery. We concluded that corpus luteum hemorrhage in women with aplastic anemia can cause therapeutic difficulties. Laparoscopy is feasible for the management of a massive intraperitoneal hemorrhage secondary to a ruptured corpus luteum in such patients.

Management of Ruptured Corpus Luteum with Hemoperitoneum in Early Pregnancy – a Case Report

“…Blood retrieved from the abdominal cavity was used for autologous transfusion. The intrauterine pregnancy was electively terminated because the pregnancy was not desired ( 8 , 9 ).…”

The predicting factors for indication of surgery in patients with hemoperitoneum caused by corpus luteum cyst rupture

“…Previous reports published the cases of hemoperitoneum caused by CLCR with various coagulopathies. Coagulation disorders included aplastic anemia 11 , 12 , factor V deficiency 13 , factor XIII deficiency 14 , congenital hypofibrinogenemia 15 , and immune thrombocytopenic purpura (ITP) 16 . There was a study in the conservative group using tranexamic acid as well as fluids and blood transfusion 7 .…”

Ruptured corpus luteum cyst in women on anticoagulant: conservative or surgical management a clinical dilemma

“…Chao W et al has reported a similar case of haemoperitoneum in a 17 years old girl with aplastic anaemia treated with surgery and treatment of blood disease. 5 Cetinkaya SE et al has reported a case of 24 years old woman with congenital afibrinogenemea with recurrent massive intraperitoneal haemorrhage due to ovulation. 6 Exploratory laparotomy was done for the first bleeding episode and subsequent episode was managed by fresh frozen plasma with blood transfusion.…”