Correction: ATX-2, The C. elegans Ortholog of Human Ataxin-2, Regulates Centrosome Size and Microtubule Dynamics

Systematic analysis ofatx-2 suppressors reveals a novel regulator of PAR-5/14-3-3sigma function during mitosis inCaenorhabditis elegans

“…Recent studies in several systems have discovered that RNA binding proteins, mRNAs, and lncRNAs function and/or localize to the centrosomes, metaphase plate, kinetochores or midbody during mitosis and are suggested to play regulatory roles during the cell cycle (Aviner et al, 2017;Blower et al, 2007;Gnazzo et al, 2016;Skop et al, 2004;Stubenvoll et al, 2016;Yokoshi et al, 2014;Zheng et al, 2010). In C. elegans, the RNA-binding proteins CAR-1, SPN-4, LARP-1, and ATX-2 are all required during mitosis (Audhya et al, 2005;Burrows et al, 2010;Gnazzo et al, 2016;Gomes et al, 2001;Squirrell et al, 2006;Stubenvoll et al, 2016), and both CAR-1 and ATX-2 are necessary for spindle midzone assembly, midbody function, and the completion of cell division (Audhya et al, 2005;Gnazzo et al, 2016;Squirrell et al, 2006). In yeast, the DEAD-box RNA helicase, Ded1/DDX3, and the 5' mRNA cap-binding protein, Cdc33/eI4FE, both mediate translation and cell cycle checkpoints (Brenner et al, 1988;Grallert et al, 2000;Kronja and Orr-Weaver, 2011).…”