“…The experimental evidence presented here delineates the involvement of Brd4 in the regulation of the master transcription factor of GC B cell development, Bcl6, and other cofactors including Irf8, Pax5 and Bach2 [7,48,49]. Bcl6 is a BTB-zinc finger family transcription repressor which is highly upregulated in GC B cells, where it regulates a broad network of direct target genes [7,12].…”