“…The used methods, including autoflourescence and chemiluminescence help in differentiating benign lesions from malignant lesions already at the clinical exam. Of these, autoflourescence device has shown to be superior to chemiluminescence and to the simple clinical examination of the lesion in detecting premalignant lesions and early malignant transformation, even though it remains undoubtable the superiority of biopsy and histological exam in diagnosis [ [97] , [98] , [99] , [100] ].…”