Correction to: First clinical symptom as a prognostic factor in systemic sclerosis: results of a retrospective nationwide cohort study

Abstract

When first published, this article inadvertently listed the RESCLE investigators individually within the author list. The names should instead have been listed within the Acknowledgements section only. The corrected author list and the updated Acknowledgements section are presented in this Correction.

Very Early Diagnosis of Systemic Sclerosis: Deciphering the heterogeneity of systemic sclerosis in the very early stages of the disease

“…9,11 We may suspect that patients with puffy hands as first SSc-related symptom might be more likely to develop a diffuse cutaneous subset, similarly to what is observed in the PRESS cohort, 6 whereas patients with RP as first SSc-related symptoms would be more likely to develop limited cutaneous SSc. 9…”

“…5,6 Nonetheless, the increased prevalence of puffy fingers in the 2021 VEDOSS publication (44.9% of relative increase) may suggest that, in this population with a majority of patients from European countries, RP is the first scleroderma-related symptom. 2,7–9 This discrepancy between European and North-American registries may reflect the variability of clinical phenotypes worldwide and strengthens the need for inclusive global international registries. Another hypothesis is that RP and puffy fingers are actually the two sides of the same coin, being two early manifestations of SSc-related vasculopathy and associated endothelial dysfunction.…”

“…9 Therefore, initial clinical presentation within the VEDOSS population may also participate in predicting the course of the disease. 9,11 We may suspect that patients with puffy hands as first SSc-related symptom might be more likely to develop a diffuse cutaneous subset, similarly to what is observed in the PRESS cohort, 6 whereas patients with RP as first SSc-related symptoms would be more likely to develop limited cutaneous SSc. 9 If RP and puffy fingers represent the two sides of the same coin, that is, SSc-related vasculopathy, the question of "what may come before endothelial dysfunction?"…”

“…2 This issue of the first scleroderma-related symptoms is of upmost importance, since data from the Spanish registry suggest that the first SSc-related symptom may have a prognostic value. 9 Therefore, initial clinical presentation within the VEDOSS population may also participate in predicting the course of the disease. 9,11 We may suspect that patients with puffy hands as first SSc-related symptom might be more likely to develop a diffuse cutaneous subset, similarly to what is observed in the PRESS cohort, 6 whereas patients with RP as first SSc-related symptoms would be more likely to develop limited cutaneous SSc.…”

Die interstitielle Lungenerkrankung bei systemischer Sklerose

“…Die interstitielle Lungenerkrankung (ILD) ist eine häufige Krankheitsmanifestation und die Hauptursache für die Morbidität und Mortalität der Patienten mit SSc 2 , 3 . Sie ist eine frühe Komplikation der SSc 4 und kann die erste klinische Organmanifestation darstellen 5 . Die meisten Patienten mit einer schweren restriktiven Lungenfunktionsstörung entwickeln diese in den ersten 5 Jahren nach Krankheitsbeginn 4 .…”