Correction to: Pharmacology of natural radioprotectors

Mun, Gil-Im; Kim, Seo Young; Choi, Eun Ae; Kim, Cha Soon; Lee, Yun‐Sil

doi:10.1007/s12272-019-01194-1

Cited by 2 publications

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“…IR-induced injury can be prevented using chemical compounds, biological agents, Chinese herbal extracts or cellular therapy ( 16 , 17 ). These measures reduce or improve radiation-induced tissue damage, and thus promote rehabilitation.…”

Section: Strategies To Reduce Radiation Injurymentioning

confidence: 99%

Radioprotective countermeasures for radiation injury (Review)

Liu

Liang

et al. 2023

Mol Med Rep

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A series of physiological and pathological changes occur after radiotherapy and accidental exposure to ionizing radiation (IR). These changes cause serious damage to human tissues and can lead to death. Radioprotective countermeasures are radioprotective agents that prevent and reduce IR injury or have therapeutic effects. Based on a good understanding of radiobiology, a number of protective agents have achieved positive results in early clinical trials. The present review grouped known radioprotective agents according to biochemical categories and potential clinical use, and reviewed radiation countermeasures, i.e., radioprotectors, radiation mitigators and radiotherapeutic agents, with an emphasis on their current status and research progress. The aim of the present review is to facilitate the selection and application of suitable radioprotectors for clinicians and researchers, to prevent or reduce IR injury.

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Section: Strategies To Reduce Radiation Injurymentioning

confidence: 99%

Radioprotective countermeasures for radiation injury (Review)

Liu

Liang

et al. 2023

Mol Med Rep

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Natural Radioprotectors on Current and Future Perspectives

Shivappa

Bernhardt

2022

Journal of Pharmacy and Bioallied Sciences

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Radiation therapy is used as the primary treatment for cancer. Eighty percent of cancer patients require radiation therapy during treatment or for medical purposes. During treatment, radiation causes various biological defects in the cells. The prevalence of cytotoxicity limits the dose used for effective treatment. This method is designed to strike a balance between removing cancer cells and protecting normal tissues. Unfortunately, effective radiation is unavailable once acute toxicity occurs during clinical radiation therapy. Therefore, a lot of research interest is needed in the discovery of radioprotective drugs to accelerate treatment to reduce this toxicity (i.e., normal tissue toxicity to cancer cell death). Radiation protectors may be chemicals or drugs that minimize the damage caused due to radiation therapy in living organisms. The determination of effective and nontoxic radiation protection is an essential goal for radiation oncologists and basic radiobiologists. However, despite the advantages, many radioprotectors were found to have disadvantages which include cost, less duration, toxicity, and effect on the central nervous system. Therefore in recent years, the focus has been diverted to finding out optimal natural products to act as radioprotectors. Natural radiation protectors are plant compounds that protect normal (noncancerous) cells from damage from radiation therapy. Natural herbal products are nontoxic with proven therapeutic benefits and have long been used to treat various diseases. In conclusion, we find that there are various radiation protectors with different purposes and mechanisms of action.

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Correction to: Pharmacology of natural radioprotectors

Abstract: We apologize that there are some errors in the references for three sentences and Table 2.

Cited by 2 publications

References 0 publications

Radioprotective countermeasures for radiation injury (Review)

Radioprotective countermeasures for radiation injury (Review)

Natural Radioprotectors on Current and Future Perspectives

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