Correction to: ROS and diseases: role in metabolism and energy supply

Yang, Shenshu; Lian, Gaojian

doi:10.1007/s11010-020-03697-8

Cited by 16 publications

(12 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recently, more and more biological functions of ROS/RNS/RSS have been elucidated, revealing the tight relationship between these small molecule neurotransmitter and various diseases. [90][91][92] In particular, AD as an intricate neuropathic disease is closely related to the abnormal fluctuations of these species. [93,94] In 2021, Kim group designed and synthesized a series of benzenesulfonylated resorufin based fluorescent probes for detection of superoxide anion (O 2 * À ).…”

Section: Ros/rns/rssmentioning

confidence: 99%

Small Molecular Fluorescent Probes for Alzheimer's Disease Associated Active Species

Tang

Wang

Liu

et al. 2023

Chemistry A European J

View full text Add to dashboard Cite

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and is the main cause of dementia worldwide. As the pathogenesis of AD is quite complicated, there is continuous attention to AD‐associated active species, such as amyloid‐β plaques, neurofibrillary tangles, metal ions, reactive oxygen/nitrogen/sulphur species, cholinesterase, viscosity, formaldehyde and so on. To this end, a series of small molecular fluorescent probes for these active species have been explored for early diagnosis and even remedy of AD. Herein, we systematacially summarize the versatile fluorescent probes mainly in recent three years, including the relationship between the structure and properties as well as the targeted diagnosis and imaging application of all these fluorescent probes. Moreover, the challenges and perspectives of the AD‐related fluorescent probes are briefly explicated. We firmly expect this review may provide guidance for constructing new AD‐relevant fluorescent probes and promote the clinical study of AD.

show abstract

Section: Ros/rns/rssmentioning

confidence: 99%

Small Molecular Fluorescent Probes for Alzheimer's Disease Associated Active Species

Tang

Wang

Liu

et al. 2023

Chemistry A European J

View full text Add to dashboard Cite

show abstract

“…However, overproduction of ROS damage cellular components (such as DNA, lipids, and proteins) leads to impaired cell function and adverse inflammatory changes. [ 2 ] Therefore, to understand the source of ROS and the cause of excess ROS are beneficial to our health. It is generally known that ROS are constantly produced in the body in daily life.…”

Section: Ros In Inflammatory Diseasesmentioning

confidence: 99%

“…[ 1 ] ROS mainly comprised of various oxidant molecules including hydrogen peroxide (H 2 O 2 ), singlet oxygen (O 2 ), superoxide (O 2 • ), and hydroxyl radicals (OH • ). [ 2 ] The balance of redox stress based on ROS is a keynote that regulates the inflammatory process, while the oxidative stress is viewed as an imbalance that induces inflammatory diseases. [ 3 ] The inherent ROS scavenging system in human body cannot defend the overproduction of ROS when the inflammatory diseases happened.…”

Section: Introductionmentioning

confidence: 99%

ROS Scavenging Biopolymers for Anti‐Inflammatory Diseases: Classification and Formulation

Zhang

Yang

et al. 2020

Adv Materials Inter

115

View full text Add to dashboard Cite

Reactive oxygen species (ROS), the byproducts of aerobic metabolism, is a class of crucial molecules in physiological processes, nevertheless, would induce a series of inflammatory responses when overexpression. Excessive or inappropriate inflammation contributes to a range of acute and chronic human inflammatory diseases. In recent years, ROS scavenging agents have been widely regarded as a kind of potential therapeutic substances due to their abilities of delaying and/or inhibiting the oxidative stress in physiological microenvironments. ROS scavenging biopolymers are a group of agents that commonly have strong ROS scavenging ability and pharmacokinetic potential compared to similar low molecular weight agents. In this review, the generation and clearance of ROS in physiological processes, as well as the effects of ROS inflammatory diseases are introduced. Furthermore, the classification, macromolecular structure, and scavenging mechanism of those antioxidant polymers are systematically described and discussed, which aim to provide a guiding theoretical reference of designing effectively ROS scavenging biopolymers for anti‐inflammatory disease therapy.

show abstract

“…However, ROS, the byproduct of aerobic respiration, can cause damage to biomacromolecules such as lipids, nucleic acids, and proteins, thereby changing their functions and causing oxidative stress. However, recent studies demonstrated that ROS can also act as a signaling molecule to regulate various signaling pathways to maintain normal development of cells [ 8 ]. It has been widely accepted that ROS can be both beneficial and lethal for cancer cells.…”

Section: Introductionmentioning

confidence: 99%

Targeting the Interplay of Autophagy and ROS for Cancer Therapy: An Updated Overview on Phytochemicals

Dong

Luo

et al. 2023

Pharmaceuticals

View full text Add to dashboard Cite

Autophagy is an evolutionarily conserved self-degradation system that recycles cellular components and damaged organelles, which is critical for the maintenance of cellular homeostasis. Intracellular reactive oxygen species (ROS) are short-lived molecules containing unpaired electrons that are formed by the partial reduction of molecular oxygen. It is widely known that autophagy and ROS can regulate each other to influence the progression of cancer. Recently, due to the wide potent anti-cancer effects with minimal side effects, phytochemicals, especially those that can modulate ROS and autophagy, have attracted great interest of researchers. In this review, we afford an overview of the complex regulatory relationship between autophagy and ROS in cancer, with an emphasis on phytochemicals that regulate ROS and autophagy for cancer therapy. We also discuss the effects of ROS/autophagy inhibitors on the anti-cancer effects of phytochemicals, and the challenges associated with harnessing the regulation potential on ROS and autophagy of phytochemicals for cancer therapy.

show abstract

Correction to: ROS and diseases: role in metabolism and energy supply

Cited by 16 publications

References 0 publications

Small Molecular Fluorescent Probes for Alzheimer's Disease Associated Active Species

Small Molecular Fluorescent Probes for Alzheimer's Disease Associated Active Species

ROS Scavenging Biopolymers for Anti‐Inflammatory Diseases: Classification and Formulation

Targeting the Interplay of Autophagy and ROS for Cancer Therapy: An Updated Overview on Phytochemicals

Contact Info

Product

Resources

About