Correction

Abstract

Variability in systemic lupus erythematosus (SLE) disease manifestations is well recognized. Lupus disease activity can range from mild to severe. Fever is a common manifestation of SLE and occurs in 36%-86% of patients. In the Modified Systemic Lupus Erythematosus Disease Activity Index (M-SLEDAI), fever is taken into account as disease activity scoring. Assessment of lupus patients with fever is an important diagnostic challenge, since the initial clinical presentation of a patient with lupus is very similar to the acute febrile phase of an infection. The attribution of fever to SLE holds only after other causes are excluded.

A comparison of the performance of the 2019 European League Against Rheumatism/American College of Rheumatology criteria and the 2012 Systemic Lupus International Collaborating Clinics criteria with the 1997 American College of Rheumatology classification criteria for systemic lupus erythematous in new-onset Chinese patients

“…14 Cytokines, such as interferon-α and interleukin-1, which are also thermogenic factors, play an essential role in the pathogenesis of lupus. 23 Fever was present in more patients with early onset compared with late-onset disease in a large Canadian study. 24 In our study, fever was reported by a proportion (39%) of participants, by 52.4% in a Euro-Lupus cohort 25 and by 34.5% in early SLE.…”