Correction: Vitetta, L.; et al. Adjuvant Probiotics and the Intestinal Microbiome: Enhancing Vaccines and Immunotherapy Outcomes. Vaccines 2017, 5, 50

Vitetta, Luis; Saltzman, Emma Tali; Thomsen, Michael; Nikov, Tessa; Hall, Sean

doi:10.3390/vaccines6020026

Cited by 6 publications

(5 citation statements)

References 2 publications

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“…Thus, this promotes the development of the intestinal mucosal immune system, activating macrophages and B lymphocytes, forming germinal centers in the intestinal mucosal lymphoid tissue, and finally, transforming B lymphocytes into plasma cells to secrete mucosal antibody IgA to mediate mucosal immunity [ 126 , 127 ]. Probiotic strains can increase the levels of anti-inflammatory cytokines such as IL-10, reduce the levels of inflammatory cytokines such as TNF-α, IL-1β, and IL-8, and exert significant effects on reducing intestinal inflammation and improving colitis [ 128 ]. Additionally, different probiotics maintain gut health in different ways.…”

Section: Mechanism Of Probiotics To Improve Fd Symptomsmentioning

confidence: 99%

Research Progress for Probiotics Regulating Intestinal Flora to Improve Functional Dyspepsia: A Review

Shen,

Xie,

et al. 2024

Foods

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Functional dyspepsia (FD) is a common functional gastrointestinal disorder. The pathophysiology remains poorly understood; however, alterations in the small intestinal microbiome have been observed. Current treatments for FD with drugs are limited, and there are certain safety problems. A class of active probiotic bacteria can control gastrointestinal homeostasis, nutritional digestion and absorption, and the energy balance when taken in certain dosages. Probiotics play many roles in maintaining intestinal microecological balance, improving the intestinal barrier function, and regulating the immune response. The presence and composition of intestinal microorganisms play a vital role in the onset and progression of FD and serve as a critical factor for both regulation and potential intervention regarding the management of this condition. Thus, there are potential advantages to alleviating FD by regulating the intestinal flora using probiotics, targeting intestinal microorganisms. This review summarizes the research progress of probiotics regarding improving FD by regulating intestinal flora and provides a reference basis for probiotics to improve FD.

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Section: Mechanism Of Probiotics To Improve Fd Symptomsmentioning

confidence: 99%

Research Progress for Probiotics Regulating Intestinal Flora to Improve Functional Dyspepsia: A Review

Shen,

Xie,

et al. 2024

Foods

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“…A patent application for stable, fast-acting liposome and micelle formulations containing terpenes, hemp oil, cannabinoids, or combinations of cannabinoids, with stability ranging from a few days (micelles) to several months (liposomes), has been filed [130]. Medlab Clinical, Australia has developed NanoCelleTM, a micelle formulation made from oils, glycerol, and nonionic surfactants, to deliver lipophilic molecules (vitamin D3, statins, testoster- one propionate, CBD) across the oral buccal mucosa, bypassing the gastrointestinal (GI) tract [131,132]. Nanomicellar formulation of synthetic cannabinoid has been shown to inhibit tumor growth and adverse psychoactive effects in a syngeneic mouse model of triple-negative breast cancer [120].…”

Section: Lipid-based Nanoformulationsmentioning

confidence: 99%

Perspectives on Challenges in Cannabis Drug Delivery Systems: Where Are We?

Palrasu¹,

Wright²,

Patel³

et al. 2022

Med Cannabis Cannabinoids

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Cannabis and its natural derivatives have emerged as promising therapeutics for multiple pathological and nonpathological medical conditions. For example, cannabinoids, the most popular and biologically active chemicals in cannabis, aid in many clinical ailments, including pain, inflammation, epilepsy, sleep disturbances or insomnia, multiple sclerosis, anorexia, schizophrenia, neurodegenerative diseases, antinausea, and most importantly, cancer. Despite the comprehensive benefits, certain aspects of cannabis present unique challenges in the medical cannabis landscape. Recent studies have highlighted the inherent challenges associated with cannabinoids' formulation like low solubility, rapid metabolism, poor bioavailability, and erratic pharmacokinetics – all of which contribute to the limited efficacy of cannabinoids. Several efforts are underway to address the bottlenecks and modify the formulations along with the delivery systems to achieve greater solubility/bioavailability, potency, and efficacy in treatment settings while minding the necessary standards for purity associated with the pharmaceutical industry. The current article presents a perspective on (1) a working knowledge of cannabinoids and their mechanisms of action, (2) the landscape of using medicinal cannabis for cancer-related medical conditions along with adversities, (3) current approaches, formulations, and challenges in medicinal cannabis delivery systems (oral, transdermal, pulmonary, and transmucosal), and lastly, (4) emerging approaches to improve delivery systems.

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“…Also, there was a substantial decrease in the population of Enterobacilli. Thus, such formulations have the potential to influence the gut flora and influence the immune system of the host [24].…”

Section: Article Articlementioning

confidence: 99%

“…Another mechanism for boosting immunity involves cell-surface bodies like capsules and fimbriae [1,5,25]. Since the pathogens and LAB both have binding sites resembling the host receptors, they compete for host pattern recognition receptors (PRRs) like tool-like receptors (TLRs) [3,4,24]. Probiotics can also inhibit the adhesion of pathogen through receptor alterations brought out by probiotic enzymes, receptor analogue production, and biosurfactant secretion [29].…”

Section: Immunity-boosting Action Activity and Mechanism Of Probioticsmentioning

confidence: 99%

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A Review on Immune-Boosting Activity of Functional Foods-Prebiotics and Probiotics

Avasare

2021

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Panoramic research on the correlation of gut microbial health and the immune system led to an increase in awareness regarding the importance of functional foods like prebiotics and probiotics. Probiotics and prebiotics possess the capability to alter the gut microflora and thereby regulating the immune system. They can positively influence gut microbiota and correspondingly improve host immunity. Prebiotics are indigestible fibres that are metabolised by gut microorganisms to produce metabolites that are beneficial to human health. Probiotics are 'good bacteria' which play a pivotal role in maintaining the gut microbiome. This review paper aims to present an overview of the human gut, immune system, and their correlation. This review also assesses the immune-boosting mechanism of probiotics and prebiotics and provides a comprehensive view of the potential of functional food-prebiotics and probiotics for boosting immunity. The review has also provided a glimpse of the potential application of prebiotics and probiotics in boosting immunity against SARS-COVID-19 and the mechanism behind it. It discusses the future scope in the formulation and application of functional prebiotic and probiotic foods. It is suggested to further the research for improving the acceptability, efficiency, and to aid in the treatment of various diseases. ARTICLE ARTICLE 2. Relationship between gut health and the immune system2.1 Overview on gut and gut microbiota

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Correction: Vitetta, L.; et al. Adjuvant Probiotics and the Intestinal Microbiome: Enhancing Vaccines and Immunotherapy Outcomes. Vaccines 2017, 5, 50

Abstract: The authors wish to make the following corrections to this paper due to a typesetting error in the conclusion of this article which was recently published in Vaccines[...]

Cited by 6 publications

References 2 publications

Research Progress for Probiotics Regulating Intestinal Flora to Improve Functional Dyspepsia: A Review

Research Progress for Probiotics Regulating Intestinal Flora to Improve Functional Dyspepsia: A Review

Perspectives on Challenges in Cannabis Drug Delivery Systems: Where Are We?

A Review on Immune-Boosting Activity of Functional Foods-Prebiotics and Probiotics

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