Correlates of quality of life among persons living with tuberculosis: A cross-sectional study

Tornu, Eric; Quarcoopome, Louisa

doi:10.1371/journal.pone.0277192

Cited by 11 publications

(8 citation statements)

References 47 publications

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“…Furthermore, their fear and self-acceptance will be easier to get through when social support is present, particularly when they are too sick [ 22 ]. This finding is inconsistent with a previous study that showed social support from family corresponded with better QoL among TB patients [ 23 ]. However, another study reported that social support was more likely to have poor QoL since those with TB considered emotional support as a burden to them and seemed to remind them that their disease could infect others [ 24 ].…”

Section: Discussioncontrasting

confidence: 99%

Determinants of quality of life among people with HIV and tuberculosis in an underserved area in Indonesia: a cross-sectional study

Sianturi,

Izzah,

Huda

et al. 2023

Pan Afr Med J

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Introduction human immunodeficiency virus (HIV) and tuberculosis (TB) remain global health problems and impose a substantial reduction in people´s quality of life (QoL). This study aimed to assess and compare the QoL in HIV and TB patients and factors associated with QoL between those groups. Methods a cross-sectional study was conducted at a hospital clinic in Jayapura, Indonesia, between December 2022 and March 2023. Those who were aged above 18 years, diagnosed with HIV or TB infection, have been taking HIV or TB medications for at least 3 months, and provided informed consent were eligible to participate. Patients´ QoL was measured using the Bahasa Indonesia version of a validated 26-item World Health Organization Quality of Life - Brief (WHOQOL-BREF) questionnaire. Results a total of 365 patients with HIV and 125 with TB were included. The majority of participants were Papuan (75.9%) and aged 20 - 65 years (92.9%). More than half of the participants were female (56.5%), employed (50.8%), married (65.5%), and had family support (64.9%). Education level and social support were predictors of poor physical health in the HIV group, while ethnicity was a predictor in the TB group. Patients´ age was associated with poor psychological health in HIV, whereas sex was the associated factor in TB patients. Ethnicity was the only predictor of poor social relationships in those with TB. Whereas patients´ age was a predictor of poor environmental health in the HIV group, marital status, and education were predictors in the TB group. Finally, only social support was associated with poor general QoL in TB patients. Conclusion tuberculosis (TB) patients had poorer QoL than those with HIV. There is a need for more awareness to support those receiving TB treatment. In addition, further research is needed to understand in more detail the determinants of patients with drug-resistant TB, TB with HIV, and drug-resistant TB-HIV, to ensure that interventions are designed to help them.

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Section: Discussioncontrasting

confidence: 99%

Determinants of quality of life among people with HIV and tuberculosis in an underserved area in Indonesia: a cross-sectional study

Sianturi,

Izzah,

Huda

et al. 2023

Pan Afr Med J

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“…It is shown in the study that Muslim patients have a significantly lower psychological QOL of -36.91 compared to those patients who are Roman Catholics. This is in line with a study by Tornu and Quarcoopome (2022), where although they did not specify what religion, they stated that TB patients who mainly receive from religious institutions result in a lower QOL not only in the psychological domain but in all four domains of QOL.…”

Section: Sociodemographic Profilesupporting

confidence: 88%

Sociodemographic Profile, Clinical Factors and Quality of Life of Multi-Drug Resistant Tuberculosis Patients in Pampanga

D. Franco,

Joseph P. Galan,

Chantel D. Manguba

et al. 2023

IJRP

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The purpose of this study was to determine the significant relationship between sociodemographic profile, clinical factors, and quality of life of patients with multidrug-resistant tuberculosis in Pampanga. It focused on residents of Pampanga, ages 18-59 years old, who have been identified as having MDR-TB (multidrug-resistant tuberculosis). The findings of this study revealed that the sociodemographic profile has a significant correlation between the Quality of Life of Multidrug-Resistant Tuberculosis patients and the Clinical Factors and Quality of Life of Multidrug-Resistant Tuberculosis patients. The results showed that patients with higher educational backgrounds are more cautious and are more knowledgeable about the disease progression and transmission, thus having a higher quality of life, and the researchers concluded that the sociodemographic profile has a significant impact on the quality of life of MDR-TB patients. As the researchers analyzed the correlation of the variables, another research can be conducted to identify the other different variables that influence the four domains of QOL of MDR-TB patients.

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“…We also observed that the EQ-5D-5L score during the intensive phase was higher among our cohort than in a study conducted in South Africa [53]. Studies have shown that family and social support for people with TB improves their quality of life [93,94].…”

Section: Quality Of Lifesupporting

confidence: 52%

Stigma, depression, and quality of life among people with pulmonary tuberculosis diagnosed through active and passive case finding in Nepal: a prospective cohort study

Dixit,

Rai,

Aryal

et al. 2024

BMC Global Public Health

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Background The psychosocial consequences of tuberculosis (TB) are key barriers to ending TB globally. We evaluated and compared stigma, depression, and quality of life (QoL) among people with TB diagnosed through active (ACF) and passive (PCF) case-finding in Nepal. Methods We prospectively recruited adults with TB diagnosed through ACF and PCF in four districts of Nepal between August 2018 and April 2019. Participants were interviewed at 8–12 weeks (baseline) and 22–26 weeks (follow-up) following treatment initiation. TB stigma was measured using an adapted Van Rie Stigma Scale (0 = no stigma to 30 = highest stigma). Depression was measured using a locally-validated Patient Health Questionnaire (PHQ-9). Mild and major depression were indicated by PHQ-9 scores 5–9 and ≥ 10, respectively. QoL was measured using the EuroQoL 5-Dimension 5-level (EQ-5D-5L) from 0 to 1 (optimal QoL); and self-rated health from 0 to 100 (optimal self-rated health). Results We recruited 221 participants (111 ACF; 110 PCF) with a mean age of 48 years (standard deviation [SD] = ± 16), of whom 147/221 (67%) were men. The mean TB stigma score was 12 (SD = 7.3) at baseline and 12 (SD = 6.7) at follow-up. The most commonly perceived elements of TB stigma at baseline were that people with TB experienced guilt (110/221, 50%) and feared disclosure outside their household (114/221, 52%). Self-rated health and EQ-5D-5L scores increased from baseline to follow-up (69.3 to 80.3, p < 0.001; 0.92 to 0.9, p = 0.009). Nearly one-third of participants (68/221, 31%) had mild or major depression at baseline. The proportion of participants with major depression decreased from baseline to follow-up (11.5% vs. 5%, p = 0.012). There was a moderate, significant positive correlation between depression and stigma scores (r = 0.41, p < 0.001). There were no differences found in TB stigma, self-rated health, QoL, or prevalence of mild/major depression between ACF and PCF participants. Conclusions We found a substantial, persistent, and clustered psychosocial impact among adults with TB diagnosed through both ACF and PCF strategies in Nepal. These findings suggest an urgent need to develop effective, evidence-based psychosocial support interventions with the potential to be integrated with existing ACF strategies and routine TB service activities.

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Correlates of quality of life among persons living with tuberculosis: A cross-sectional study

Cited by 11 publications

References 47 publications

Determinants of quality of life among people with HIV and tuberculosis in an underserved area in Indonesia: a cross-sectional study

Determinants of quality of life among people with HIV and tuberculosis in an underserved area in Indonesia: a cross-sectional study

Sociodemographic Profile, Clinical Factors and Quality of Life of Multi-Drug Resistant Tuberculosis Patients in Pampanga

Stigma, depression, and quality of life among people with pulmonary tuberculosis diagnosed through active and passive case finding in Nepal: a prospective cohort study

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