Correlates of rehospitalisation in schizophrenia

Dey, Sangeeta; Menkes, David B; Obertová, Zuzana; Chaudhuri, Sreemanti; Mellsop, Graham

doi:10.1177/1039856216632395

Cited by 8 publications

(5 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We included 37 studies in the meta‐analysis : three randomised controlled trials and 34 observational studies (Table ). Studies were published between 1990 and 2016.…”

Section: Resultsmentioning

confidence: 99%

“…Overall, of the 34 observational studies included in the review, five were considered good quality, 21 were considered moderate quality, and eight were considered poor quality on the Newcastle–Ottawa Scale. Studies were considered poor if they included less than 20 people prescribed clozapine or failed to provide any participant characteristics, for example age, gender distribution, or dose.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

The impact of clozapine on hospital use: a systematic review and meta‐analysis

Land

Siskind

McArdle

et al. 2017

Acta Psychiatr Scand

101

View full text Add to dashboard Cite

The impact of clozapine on hospital use: a systematic review and metaanalysis.Objective: The objective of this study was to perform a systematic review and meta-analysis of studies reporting the impact of clozapine on hospital use in people with a psychotic illness. Method: PubMed, EMBASE, PsycINFO and the Cochrane Schizophrenia Group Trials Register were systematically searched from inception to 12 October 2016. We included all trials and observational studies, except case reports. Results: Thirty-seven studies were included. Clozapine significantly reduced the proportion of people hospitalised compared to control medicines (RR = 0.74; 95% CI: 0.69-0.80, P < 0.001, 22 studies, n = 44 718). There were significantly fewer bed days after clozapine treatment compared to before clozapine treatment in both controlled (MD = À34.41 days; 95% CI: À68.22 to À0.60 days, P = 0.046, n = 162) and uncontrolled studies (MD = À52.86 days; 95% CI: À79.86 days to À25.86 days, P < 0.001, n = 2917). Clozapine and control medicines had a similar time to rehospitalisation (À19.90 days; 95% CI: À62.42 to 22.63 days, P = 0.36). Conclusion: Clozapine treatment reduced the number of people hospitalised and the number of bed days after treatment compared with before treatment. Clozapine has the potential to reduce acute hospital use among people with treatment refractory schizophrenia.

show abstract

“…We included 37 studies in the meta‐analysis : three randomised controlled trials and 34 observational studies (Table ). Studies were published between 1990 and 2016.…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

The impact of clozapine on hospital use: a systematic review and meta‐analysis

Land

Siskind

McArdle

et al. 2017

Acta Psychiatr Scand

101

View full text Add to dashboard Cite

show abstract

“…Younger age and male gender were the most common factors associated with readmissions to hospitals in nearly all the studies, and across different cultures [e.g. Øiesvold et al (2000) in Norway, Mahendran et al (2005) in Singapore, Woo et al (2006) in USA, Lin et al (2010) and Hung et al (2017) in Taiwan, Dey et al (2016) in New Zealand and Chen et al (2018) in Canada]. Variables that are reflective of social determinants such as, education level, employment and housing were also predictive of rehospitalization (Lay et al 2006;Schmutte et al 2010;van der Post et al 2014).…”

Section: Introductionmentioning

confidence: 95%

The association between family dysfunction and admission to an acute mental health inpatient unit: a prospective study

Tan

Conlon

Tsamparli

et al. 2019

Ir. j. psychol. Med.

View full text Add to dashboard Cite

Objectives:With the shift from deinstitutionalization to community care in mental health services, relatives of persons with severe and enduring mental illnesses have had to take over the role as primary caregivers. Disturbed family dynamics have been observed within families with an ‘ill’ member. Although schizophrenia and related mental illnesses are biologically based disorders, environmental stress (including stress within family relationships) plays a major role in the onset and maintenance of symptoms. With this study, we assume that family dynamics play a central role in the course of severe psychiatric illness and hypothesized that dysfunction within family systems is a prognostic indicator of hospitalization in the course of schizophrenia/bipolar and schizoaffective disorders.Methods:Prospective, observational cohort study evaluating family functioning of 121 patients (schizophrenia/bipolar and schizoaffective disorder) from community at baseline and followed-up over 12-month period after recruitment. Measurements included demographics, diagnosis, Family Assessment Device – General Functioning, Perceived Criticism Scale, Brief Psychiatric Rating Scale, Global Assessment of Functioning and Social Support Questionnaire-6.Results:Significant differences found between patients admitted and not admitted during the 12-month time period for age (p = 0.003), Brief Psychiatric Rating Scale (BPRS; p = 0.026), Family Assessment Device – General Functioning (FAD-GF; p = 0.007) and Social Support Questionnaire total satisfaction level (p = 0.042) at baseline. Bivariate analysis showed that those admitted into hospital were younger with a higher BPRS score, less social satisfaction and disturbed family dynamics. FAD-GF (p = 0.006) and age (p = 0.022) were significant independent predictors for admission.Conclusion:This provides further evidence supporting importance of promoting better family functioning through modified family dynamics, integrating and involving family into the care of such patients.

show abstract

“…Recent data on readmission rates among youths showed that more than 30% of young patients are readmitted to acute psychiatric inpatient units within one year after discharge, regardless of their diagnosis of admission [ 18 ]. Regarding psychotic disorders, early readmission can be considered an indicator of psychopathological vulnerability [ 19 ]. A recent meta-analysis focusing on psychiatric readmission of children and adolescents identified suicidal ideation at first admission, prior hospitalization, and discharge from a residential treatment as factors associated with relapse [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

Predictors of Readmission in Young Adults with First-Episode Psychosis: A Multicentric Retrospective Study with a 12-Month Follow-Up

Besana,

Civardi,

Mazzoni

et al. 2024

Clinics and Practice

View full text Add to dashboard Cite

Background: A significant number of young individuals are readmitted one or more times shortly after their first episode of psychosis. Readmission may represent a marker of psychopathological vulnerability. Our primary aim was to evaluate the impact of clinical and socio-demographic variables on readmission at 12-month follow-up. Secondly, our goal was to determine whether the use of Long-Acting Injection (LAI) antipsychotics provides notable benefits compared to oral medications in preventing subsequent readmissions. Subjects and methods: 80 patients hospitalised for the first time with a diagnosis of psychotic disorder (ICD-10 criteria) were retrospectively assessed through clinical records. The mean age was 21.7 years. Patients were predominantly male (n = 62, 77.5%), and 55 subjects had at least 8 years of education. 50% of the sample was “NEET” (not in education, employment, or training). Results: 35 patients (43.8%) were discharged with a LAI antipsychotic, while 45 (56.2%) recieved oral antipsychotic therapy. Substance use (p = 0.04) and oral antipsychotics at discharge (p = 0.003) were significantly associated with readmission at 1 year. We did not find any significant predictors of being discharged with LAI therapy. Conclusion: Our findings underlined the importance of identifying patients at risk of readmission in order to prevent future rehospitalization and promote appropriate prevention strategies. LAIs should be considered as a first-choice treatment for patients hospitalised for FEP since they proved to be effective in preventing relapse.

show abstract

Correlates of rehospitalisation in schizophrenia

Cited by 8 publications

References 15 publications

The impact of clozapine on hospital use: a systematic review and meta‐analysis

The impact of clozapine on hospital use: a systematic review and meta‐analysis

The association between family dysfunction and admission to an acute mental health inpatient unit: a prospective study

Predictors of Readmission in Young Adults with First-Episode Psychosis: A Multicentric Retrospective Study with a 12-Month Follow-Up

Contact Info

Product

Resources

About