Correlates of sexual desire in post-menopausal women

Bachmann, Gloria; Leiblum, Sandra R.; Sandler, Bernard; Ainsley, William; Narcessian, Robert; Shelden, Robert M.; Hymans, Hanna Nakajima

doi:10.1016/0378-5122(85)90042-8

Cited by 50 publications

(21 citation statements)

References 11 publications

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“…One of the common complaints in transient menopause-menopause period is physical complaint, where 80% of females in the study group suffered from physical problems, which were significantly associated with reduction in sexual desire, a finding consistent with other studies (6,16,17). This study found no significant relationship between hot flashes and vaginal dryness, and decreased sexual desire, a finding similar to the studies of Gracia et al and Reed et al (17,18).…”

Section: Discussionsupporting

confidence: 82%

“…This study found no significant relationship between hot flashes and vaginal dryness, and decreased sexual desire, a finding similar to the studies of Gracia et al and Reed et al (17,18). However, Mohammad Alizadeh charandabiee et al and some other studies indicated a marked relationship between hot flashes, night sweating, and reduced sexual desire (6,14). Some studies indicated that decreased vaginal lubrication resulting from lower level of estrogen at this age, and associated dyspareunia caused sexual desire reduction which was in contrast to our findings (17)(18)(19).…”

Section: Discussionsupporting

confidence: 64%

“…There was no statistically significant relationship between the amounts of FSH higher than 20 mµ/ml and estradiol lower than 40 pg/mL with sexual desire reduction. Longitudinal studies on females aged 45 and more, conducted by Dennerstein et al and by Bachmann et al showed no significant relationship between lower level of estrogen and decreased sexual desire in all stages of menopause (6,21). However, the role of estrogen and androgen was considered important by other studies (3, 7).…”

Section: Discussionmentioning

confidence: 99%

“…Although it seems that increasing age and hormonal changes are not the only effective factors in decreasing sexual desire. In this context, individual general health status, mental health, psychological problems and stress play effective roles in sexual desire, regardless of ageing and the status of menopause (6,7). Despite the important role of sexual desire in maintaining the relations between couples and preventing feeling old which unconsciously affects the quality of life, there have been few researches conducted on the subject in Iran.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of Factors Affecting Sexual Desire During Menopausal Transition and Post Menopause

Rabiei¹,

Nasirie²,

Zafarqandie³

2014

Women's Health Bull

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Background:One of the most common problems of women especially during transient menopause and post menopause is reduction in sexual desire which affects their social and psychological health. Objectives: The present study attempted to evaluate the impact of some personal and social factors, common age-related complaints, and follicular stimulating hormone and estradiol on sexual desire. Patients and Methods:This cross-sectional study was conducted on 201 females, aged 45-60 years old, without any history of psychological illness, and not receiving any hormone therapy including estrogen-progesterone. They filled three questionnaires; menopausal rating scale (MRS), symptom checklist 90 and their sexual interests and demographic characteristics. The data were analyzed using Pearson Chisquare tests and logistic regression (using SPSS 18). Results: A deceasing sexual desire was observed in 34.7% of the cases. A statistically significant relationship was found between reduced sexual desire and physical complaints and mood changes including anxiety and depression. Women who were widowed or divorced exhibited a significantly higher reduction in sexual desire. There was a significant correlation between sexual satisfaction and sexual desire. However, no significant relationship was observed between sexual desire and hot flashes, dyspareunia and level of estradiol and FSH. Conclusions: Mental and physical health of women and their sexual satisfaction play a more effective role in predicting sexual desire, regardless of age and hormonal changes during this period.

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Section: Discussionsupporting

confidence: 82%

Section: Discussionsupporting

confidence: 64%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Evaluation of Factors Affecting Sexual Desire During Menopausal Transition and Post Menopause

Rabiei¹,

Nasirie²,

Zafarqandie³

2014

Women's Health Bull

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“…For example, mood, energy, muscle mass, and strength improve with androgen therapy and might, therefore, contribute indirectly to the observed beneficial effects of androgens on sexual functioning (Grinspoon et al, 2000). Second, the results of basal hormone studies are inconsistent, since men and women with low sex hormone levels do not uniformly report low levels of sexual function (Travison et al, 2006;Santoro et al, 1996;Burger et al, 1995Burger et al, , 1999Burger et al, , 2000Leiblum et al, 2006;Sternbach, 1998;Bachmann et al, 1985;Greendale et al, 1996;Davidson et al, 1983;Vermeulen, 2001). Finally, a substantial proportion of both men and women (30-50%) report no change in libido after medical or surgical castration despite obvious losses of reproductive endocrine function (Bagatell et al, 1994;Bremer, 1959;Dennerstein et al, 1977Dennerstein et al, , 2002Chakravarti et al, 1977;Tauber, 1940;Elit et al, 2001;Madalinska et al, 2005;Zussman et al, 1981).…”

Section: Introductionmentioning

confidence: 89%

Pharmacologically Induced Hypogonadism and Sexual Function in Healthy Young Women and Men

Schmidt

Steinberg

Negro

et al. 2008

Neuropsychopharmacol

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Studies fail to find uniform effects of age-related or induced hypogonadism on human sexual function. We examined the effects of induced hypogonadism on sexual function in healthy men and women and attempted to identify predictors of the sexual response to induced hypogonadism or hormone addback. The study design used was a double-blind, controlled, crossover (self-as-own control). The study setting was an ambulatory care clinic in a research hospital, and the participants were 20 men (average ± SD age ¼ 28.5 ± 6.2 years) and 20 women (average ± SD age ¼ 33.5 ± 8.7 years), all healthy and with no history of psychiatric illness. A multidimensional scale assessing several domains of sexual function was the main outcome measure. Participants of the study received depot leuprolide acetate (Lupron) every 4 weeks for 3 months (men) or 5 months (women). After the first month of Lupron alone, men received (in addition to Lupron) testosterone enanthate (200 mg intramuscularly) or placebo every 2 weeks for 1 month each. Women received Lupron alone for 2 months, and then, in addition to Lupron, they received estradiol and progesterone for 5 weeks each. The results of the study: in women, hypogonadism resulted in a significant decrease in global measures of sexual functioning, principally reflecting a significant decrease in the reported quality of orgasm. In men, hypogonadism resulted in significant reductions in all measured domains of sexual function. Testosterone restored sexual functioning scores in men to those seen at baseline, whereas neither estradiol nor progesterone significantly improved the reduced sexual functioning associated with hypogonadism in women. Induced hypogonadism decreased sexual function in a similar number of men and women. No predictors of response were identified except for levels of sexual function at baseline. In conclusion, our data do not support a simple deficiency model for the role of gonadal steroids in human sexual function; moreover, while variable, the role of testosterone in sexual function in men is more apparent than that of estradiol or progesterone in women.

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