Correlating the efficacy of knee viscosupplementation with osteoarthritic changes on roentgenological examination

Toh, Eugene; Prasad, Pancham; Teanby, D.N.

doi:10.1016/s0968-0160(02)00040-6

Cited by 32 publications

(14 citation statements)

References 16 publications

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“…This raises two problems: what advice to give individual patients on the chances of pain and disability reduction following the course of injections, and which patients to select for injection. Previous reports have suggested that patients with advanced structural disease are unlikely to benefi t (Toh et al, 2002). In our study, x-ray severity did not appear to be linked to clinical response.…”

Section: Discussioncontrasting

confidence: 54%

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Clinical outcomes from a physiotherapist‐led intra‐articular hyaluronic acid injection clinic

Birchall

Ismail

Peat

2008

Musculoskeletal Care

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Section: Discussioncontrasting

confidence: 54%

“…Over two years, it was hoped to be able to recruit at least a suffi cient number of patients to compare with previous hospitalbased cohorts (e.g. Toh et al, 2002; n = 60).…”

Section: Discussionmentioning

confidence: 99%

Clinical outcomes from a physiotherapist‐led intra‐articular hyaluronic acid injection clinic

Birchall

Ismail

Peat

2008

Musculoskeletal Care

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“…Despite clinical evaluations, age, symptoms, and disease severity have not proven helpful in identifying the patients who might benefit the most. Some studies suggest that patients older than 65 years and with those with advanced radiographic stage arthritis were less likely to benefit from intra-articular injection of HA [13,18]. However, other studies have suggested the opposite, in favor of an older population with more severe knee disease, as these patients may be more sensitive in detecting an analgesic effect [19, 20].…”

Section: Discussionmentioning

confidence: 99%

Intra-Articular Hyaluronic Acid as Treatment in Elderly and Middle-Aged Patients with Knee Osteoarthritis

Uçar

Dıraçoğlu²,

Süleyman

et al. 2013

TORJ

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Introduction: Osteoarthritis is the most common age-related degenerative joint disease. It affects all the joints containing hyaline cartilage. Knee osteoarthritis is the most cumbersome in terms of prevalence and disability. The aim of this study to evaluate the efficacy of intra-articular hyaluronic acid in patients with knee osteoarthritis with regard to joint pain and function, as well as patient satisfaction, assessed at one month and at one year, and by age group.Methods:In this prospective randomised study, 172 patients who were diagnosed knee OA and who received three consecutive intra-articular injections of HA weekly were included. Patients 65 years of age or older were accepted as the “elderly group”, and those under 65 were accepted as the “middle-aged group”. Clinical evaluations of efficacy and safety were conducted at the beginning of the study, one month after the third injection, and one year after the third injection.Results:In the two groups, the intragroup analysis revealed significant improvements following injection when compared with preinjection values. According to the last followup controls (after 12 months) in the middle-aged group, VAS activity pain, VAS rest pain, WOMAC physical function, and WOMAC pain values were found to be statistically lower when compared with pre-injection values. In the elderly group, no statistically significant differences were found between pre-injection and after 12 months.Conclusion:We can conclude that intra-articular joint HA injections are effective in both young and old patients with OA with regard to pain and functional status over a short-term period. Further, HA injections in patients younger than 65 years can be planned for a one-year period.

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“…De ce point de vue, il faut remarquer que la majorité des cas de rhizarthrose radiologiquement sévère était dans le groupe 1, même si cela n'était pas statistiquement significatif. En effet, la réponse au traitement dépend probablement des lésions radiologiques comme l'ont montré Toh et al [14] pour le genou. Le délai plus court entre la dernière infiltration et la première évaluation à un mois dans le groupe 3 pourrait expliquer la réponse plus importante observée dans ce groupe.…”

Section: Discussionunclassified

Infiltration intra-articulaire d'acide hyaluronique dans l'articulation trapézométacarpienne du pouce. Évaluation prospective de l'efficacité dans la rhizarthrose

Roux

Fontas

Breuil

et al. 2007

Revue du Rhumatisme

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Correlating the efficacy of knee viscosupplementation with osteoarthritic changes on roentgenological examination

Cited by 32 publications

References 16 publications

Clinical outcomes from a physiotherapist‐led intra‐articular hyaluronic acid injection clinic

Clinical outcomes from a physiotherapist‐led intra‐articular hyaluronic acid injection clinic

Intra-Articular Hyaluronic Acid as Treatment in Elderly and Middle-Aged Patients with Knee Osteoarthritis

Infiltration intra-articulaire d'acide hyaluronique dans l'articulation trapézométacarpienne du pouce. Évaluation prospective de l'efficacité dans la rhizarthrose

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