2023
DOI: 10.3390/antiox12030715
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Correlation Analysis between Dietary Intake of Tyrosols and Their Food Sources and Urinary Excretion of Tyrosol and Hydroxytyrosol in a European Population

Abstract: This study analyzed the correlations between the acute and habitual intake of dietary tyrosols, their main food sources, and 24 h urine excretions of tyrosol (Tyr) and hydroxytyrosol (OHTyr) in participants from the European Prospective Investigation into Cancer and Nutrition study (EPIC). Participants (n = 419) were healthy men and women aged from 34 to 73 years from 8 EPIC centers belonging to France, Italy, and Germany. Acute and habitual dietary data were collected using a standardized 24 h dietary recall … Show more

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“…This metabolite was used as a biomarker of compliance with the intervention (MedDiet + VOO) in the PREDIMED study [ 12 ] and its biological metabolite (homovanillyl alcohol) was associated with a lower risk of CVD and total mortality [ 34 ]. In the EPIC cohort, urinary hydroxytyrosol was also correlated with total olive oil intake [ 35 ]. Unfortunately, our metabolomic platform does not allow us to determine plasma phenolic compounds.…”
Section: Discussionmentioning
confidence: 99%
“…This metabolite was used as a biomarker of compliance with the intervention (MedDiet + VOO) in the PREDIMED study [ 12 ] and its biological metabolite (homovanillyl alcohol) was associated with a lower risk of CVD and total mortality [ 34 ]. In the EPIC cohort, urinary hydroxytyrosol was also correlated with total olive oil intake [ 35 ]. Unfortunately, our metabolomic platform does not allow us to determine plasma phenolic compounds.…”
Section: Discussionmentioning
confidence: 99%