Correlation analysis between myocardial work indices and liver function classification in patients with hepatitis B cirrhosis: A study with non-invasive left ventricular pressure-strain loop

Cao, Yang; Zhang, Huihui; Li, Shuai; Li, Siliang; Sun, Shuowen; Chen, Jinwen; Ye, Ting; Zhang, Xijun; Yuan, Jianjun

doi:10.3389/fcvm.2023.1126590

Cited by 2 publications

(1 citation statement)

References 33 publications

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“…Studies published later, when guidelines for GLS measurement were more standardized, yielded varying results. Most studies did not find statistically significant differences between patients and controls [38,40,41], while some studies found lower absolute values for patients with cirrhosis than for controls [37,42]. Some studies even found increased GLS values in cirrhotic patients compared to controls.…”

Section: How Different Are Left Ventricular Strain Values Of Cirrhoti...mentioning

confidence: 99%

The Contemporary Role of Speckle Tracking Echocardiography in Cirrhotic Cardiomyopathy

Dimitroglou,

Aggeli,

Alexopoulou

et al. 2024

Life

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Cirrhotic cardiomyopathy (CCM) is characterized by elevated cardiac output at rest, an inability to further increase contractility under stress, and diastolic dysfunction. The diagnosis of CCM is crucial as it can lead to complications during liver transplantation. However, its recognition poses challenges with conventional echocardiography techniques. Speckle tracking echocardiography (STE), particularly global longitudinal strain (GLS), is a novel index that enhances the diagnostic efficacy of echocardiography for both ischemic and non-ischemic cardiomyopathies. GLS proves more sensitive in identifying early systolic dysfunction and is also influenced by advanced diastolic dysfunction. Consequently, there is an expanding scope for GLS utilization in cirrhotic cases, with newly updated diagnostic criteria for CCM incorporating GLS. Specifically, systolic dysfunction is now defined as either a left ventricular ejection fraction below 50% or an absolute GLS below 18%. However, conflicting data on GLS alterations in liver cirrhosis patients persist, as many individuals with advanced disease and a poor prognosis exhibit a hyperdynamic state with preserved or increased GLS. Consequently, the presence of CCM, according to the updated criteria, does not exhibit a significant association—in the majority of studies—with the severity of liver disease and prognosis. Furthermore, information on other indices measured with STE, such as left atrial and right ventricular strain, is promising but currently limited. This review aims to offer a critical assessment of the existing evidence concerning the application of STE in patients with liver cirrhosis.

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Section: How Different Are Left Ventricular Strain Values Of Cirrhoti...mentioning

confidence: 99%

The Contemporary Role of Speckle Tracking Echocardiography in Cirrhotic Cardiomyopathy

Dimitroglou,

Aggeli,

Alexopoulou

et al. 2024

Life

View full text Add to dashboard Cite

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Application of the Left Ventricular Pressure–Strain Loop Technique in Monitoring Improvement Factors of Patients With Heart Failure Reduced Ejection Fraction

Li,

Guo,

Tang

et al. 2024

Cardiovascular Therapeutics

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The left ventricular pressure–strain loop (PSL) is a new technique based on ultrasound for noninvasive quantitative evaluation of global and local myocardial work (MW). This study is aimed at evaluating improvement factors of patients with heart failure (HF) reduced ejection fraction (HFrEF) using the PSL technique. A total of 88 patients with HF were enrolled in this study, which had ≤ 40% left ventricular ejection fraction (LVEF). The EchoPAC workstation was used to obtain the global longitudinal strain (GLS) and MW parameters of the left ventricle. All patients have taken medicines for HF treatments for 6–12 months. The improvements of HF after therapies were evaluated according to the following recommended criteria. The clinical characteristics of patients with improved and nonimproved groups were stratified via univariate or multivariate logistic regression analysis, receiver operating characteristic (ROC), and the area under ROC (area under the curve (AUC)). There were no significant differences in general medical information, the underlying diseases, laboratory findings, myocardial enzyme activities, and taking medicines between the improved and nonimproved LVEF patients (p > 0.05). There were significant differences in LVEF of patients at admission, left ventricular end‐diastolic diameter (LVEDD), interventricular septum thickness (IVST), early diastolic mitral flow peak velocity E (E peak), GLS, global myocardial work index (GWI), global myocardial constructive work (GCW), and global myocardial work efficiency (GWE) between the two groups (p < 0.05). Univariate and multivariate logistic regression analyses confirmed that GWI and GCW were critical predictive factors for LVEF improvement in patients with HF. ROC curve showed that the AUC of GWI and GCW were 0.796 and 0.779 at the cut‐off of 741 mmHg% for GWI and 973.5 mmHg% for GCW, respectively. The sensitivities of GWI and GCW were 65% and 75%, and the specificities of GWI and GCW were 83.3% and 79.2% at given cut‐off values. These results revealed that GWI and GCW were independent predictors of improvement of LVEF in patients with HFrEF.

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Correlation analysis between myocardial work indices and liver function classification in patients with hepatitis B cirrhosis: A study with non-invasive left ventricular pressure-strain loop

Cited by 2 publications

References 33 publications

The Contemporary Role of Speckle Tracking Echocardiography in Cirrhotic Cardiomyopathy

The Contemporary Role of Speckle Tracking Echocardiography in Cirrhotic Cardiomyopathy

Application of the Left Ventricular Pressure–Strain Loop Technique in Monitoring Improvement Factors of Patients With Heart Failure Reduced Ejection Fraction

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