Correlation between blood rheological properties and red blood cell indices(MCH, MCV, MCHC) in healthy women

Abstract

Cell volume and haemoglobin content had a strong impact on deformability in apparently healthy mid age women, whereas low MCHC and large MCV were associated with an increase in deformability while high MCHC and small MCV correlated with increased rigidity of RBC. BMI had no impact on deformability while age was associated with an increase in all determinants of blood viscosity. RBC aggregability was not affected by MCV, MCHC or MCH in mid-age women.

Impact of Type of Sport, Gender and Age on Red Blood Cell Deformability of Elite Athletes

“…These findings suggest that the low deformability values found in young athletes were associated to lower MCV while higher MCV of adult athletes might cause the increase in RBC deformability. These results are line with the similar findings in RBC deformability as RBC deformability and MCV correlate [34].…”

Effectiveness of AOS–iron on iron deficiency anemia in rats

“…45 Hence, MCV, MCH and MCHC are collectively referred to as the average red blood cell index. 46 As shown in Table 1, MCV, MCH and MCHC in the anemia model group were signicantly reduced (p < 0.05) in comparison with the normal control group. In fact, owing to iron deciency, the Hb content in RBC was reduced, which resulted in a decrease in cell volumes.…”

Inherited thrombophilia and reproductive disorders

“…Inherited thrombophilia constitutes a group of abnormalities of blood coagulation, including the factor V Leiden mutation (FVL) (homozygous or heterozygous), the prothrombin (FII) G20210A mutation (Pm) (homozygous or heterozygous), and deficiencies of the endogenous anticoagulants, antithrombin (AT), protein C, and protein S. Among these conditions, FVL and Pm are relatively common, while the others are rare. FVL is a point mutation (G1691A), resulting in an altered factor resistant to inactivation by protein C. The Pm leads to a 20%-50% increase in plasma prothrombin levels (2,3). The prevalence of inherited thrombophilia in the general western population is estimated to be approximately 15% (4).…”