Correlation between blue-on-yellow perimetry and scanning laser polarimetry with variable corneal compensation measurements in primary open-angle glaucoma

Zhong, Yong; Chen, Liping; Cheng, Yu; Huang, Ping

doi:10.1007/s10384-009-0726-z

Cited by 7 publications

(5 citation statements)

References 33 publications

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“…Those who were less than 18 years old were also excluded. POAG was diagnosed according to the presence of typical glaucomatous abnormal optic nerve changes (localized optic disc notching, thinning or vertical cup-to-disc ratio asymmetry of > 0.2 between eyes, or localized wedge-shaped retinal nerve fiber layer defect) associated with matching glaucomatous visual field defects with standard automated perimetry (SAP), untreated IOP >21 mmHg with Goldmann applanation tonometer (GAT) in at least one eye, open angle on gonioscopy and no clinically apparent secondary cause for their glaucoma [ 16 ]. OHT was defined as having normal optic nerve head and retinal nerve fiber layer, normal visual field with SAP, untreated IOP >21 mmHg with GAT in at least one eye, open angle on gonioscopy and no clinically apparent secondary cause for high IOP [ 17 ].…”

Section: Methodsmentioning

confidence: 99%

Short-Term Reproducibility of Twenty-Four-Hour Intraocular Pressure Curves in Untreated Patients with Primary Open-Angle Glaucoma and Ocular Hypertension

Qin

Cheng

et al. 2015

PLoS ONE

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PurposeTo assess the short-term day-to-day reproducibility of 24-hour intraocular pressure (IOP) curves in various respects in untreated primary open-angle glaucoma (POAG) and ocular hypertension (OHT) patients.Methods47 subjects with POAG and 34 subjects with OHT underwent IOP measurements every 2 hours in both eyes for consecutive 48 hours by a non-contact tonometer (NCT). IOP values at each time point were recorded. Mean IOP, peak IOP, time difference of peak IOP between two days and IOP fluctuation were also calculated. Intraclass correlation coefficients (ICCs) and Bland-Altman plots were used to evaluate reproducibility.ResultsICCs of the entire IOP values for a complete 24-hour curve were 0.577 and 0.561 in POAG and OHT patients, respectively. ICCs of IOP values at different time points ranged from 0.384 (10am) to 0.686 (4am) in POAG patients and from 0.347 (6am) to 0.760 (4am) in OHT patients. ICCs of mean IOP, peak IOP and IOP fluctuation were respectively 0.832, 0.704, 0.367 in POAG patients and 0.867, 0.816 0.633 in OHT patients. Only 37.23% and 35.29% of the peak IOP time points appeared within the time difference of 2 hours in POAG and OHT patients, respectively, while 53.19% and 48.53% appeared within 4 hours in POAG and OHT patients, respectively.ConclusionA 24-hour IOP curve in a single day is not highly reproducible in short-term and has limited use for evaluating individual IOP condition. Mean IOP and peak IOP for a 24-hour IOP curve are useful parameters in clinical follow-up, while IOP value at a certain time point, IOP fluctuation and peak IOP time point should be interpreted with caution.

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Section: Methodsmentioning

confidence: 99%

Short-Term Reproducibility of Twenty-Four-Hour Intraocular Pressure Curves in Untreated Patients with Primary Open-Angle Glaucoma and Ocular Hypertension

Qin

Cheng

et al. 2015

PLoS ONE

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“…Standard argon laser treatments (ALT and SLT) increased the aqueous outflow through the trabecular meshwork causing coagulative and structural damage with an increased inflammatory response and pigment dispersion frequently causing transient IOP spikes and ocular discomfort [10][11][12][13][14][15][16]. MLT has been recorded to stimulate a biological response without causing any macroscopic or microscopic changes in the trabecular meshwork, thereby inducing less inflammation and reducing tissue damage [24,25]; this was also confirmed by a histologic analysis performed on human corneoscleral rim tissue from cadaver eyes [26].…”

Section: Discussionmentioning

confidence: 99%

“…Over the years, several studies confirmed the positive effects in controlling IOP and favored its diffusion. However, despite proving effective in controlling IOP, normal ocular tissue function has been found to be altered by thermal damage to the trabecular meshwork and its application was limited by several complications resulting from its use, including pressure spikes higher than 10 mmHg in 12% of patients; late spikes, especially in pseudo-exfoliative glaucoma; peripheral anterior synechiae in 15-20% of cases; and damage to the corneal endothelium [10,11].…”

Section: Introductionmentioning

confidence: 99%

Micropulse Laser Trabeculoplasty with 577 nm Wavelength at 1500 or 1000 mW for Primary Open-Angle Glaucoma: A Pilot Study

Verdina

Gironi

Battaglia

et al. 2023

Life

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Aim: To investigate the efficacy and safety of micropulse laser trabeculoplasty (MLT) using a 577 nm yellow wavelength laser randomly assigned to either 1500 or 1000 mW in patients with primary open-angle glaucoma (POAG). Methods: A prospective, double-blinded study of POAG patients was performed in a single center. MLT treatment included a 577 nm micropulse laser (IRIDEX IQ 577TM, IRIDEX, Mountain View, CA, USA) to 360° of the trabecular meshwork at randomly assigned varying powers: 1500 mW in one eye (MLT 1500 group) and 1000 mW in the other (MLT 1000 group). Best-corrected visual acuity (BCVA), intraocular pressure (IOP), corneal central thickness (CCT), and endothelial cell count (ECC) were evaluated at baseline (T0), post-operative 1 h (T1), 24 h (T2), 1 month (T3), 3 months (T4), and 6 months (T5) after laser treatment. Topical medications were assessed pre-treatment and at T4. Results: Among the 18 eyes included, we achieved a success rate (IOP reduced > 20%) in 77% of sampled eyes. In particular, IOP reduced at T2 and T3 with both MLT 1500 and 1000 without any significant differences (IOP reduction 22.9% vs. 17.3%, respectively, MLT1500 vs. MLT1000 at T2). The IOP returned to baseline values at T4 and T5 in both groups, with a reduction in topical medications administered from 2.5 ± 1.1 to 2.0 ± 1.2 to the 1500 mW group and from 2.4 ± 1.0 to 1.9 ± 1.0 to the 1000 mW group. At 1 h post-laser treatment, a transient IOP spike was registered among the MLT1500 group. There were no differences in CCT and ECC at any timepoint according to the laser powers. Conclusions: Over a 6-month follow-up period, 577 nm MLT at either 1500 or 1000 mW reduces IOP, enabling a stable reduction in the number of topical medications required for patients treated for POAG without any significant difference in terms of effectiveness and safety.

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“…[2][3][4][5] Therefore, early POAG diagnosis has been one of the many clinical problems associated with glaucoma. Increasing numbers of studies have revealed that optic disc morphological changes and visual field defects are important indicators of glaucoma diagnosis, 6,7 as well as a conditional assessment tool. The use of advanced equipment makes a detailed assessment of optic disc morphological changes and visual field defects possible.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Heidelberg retina tomography, optical coherence tomography and Humphrey visual field in early glaucoma diagnosis

et al. 2013

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Objective: To determine the value of optic disc parameters and perimetric defects in the early diagnosis of patients with primary open-angle glaucoma (POAG). Methods: Optic disc parameters and perimetry were compared among patients in the early stage of POAG, patients with suspected POAG and healthy control subjects, using Heidelberg retina tomography (HRT-II), optical coherence tomography (OCT) and a Humphrey 750i automatic field analyser, in order to determine whether these parameters could be used for early POAG diagnosis. Results: A total of 55 participants were enrolled in the study. Significant differences in the optic disc parameter and perimetry values were observed between the three groups. HRT-II parameters showed good correlation with OCT parameters. The majority of the HRT-II and OCT parameters showed a good correlation with perimetry values. Conclusions: HRT-II and OCT optic disc parameters both reflect morphological changes of the optic disc. These current findings suggest that they can both detect glaucomatous optic neuropathy earlier than a white-on-white perimetry examination. In addition, OCT can detect optic disc parameter changes that cannot be detected by HRT-II.

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Correlation between blue-on-yellow perimetry and scanning laser polarimetry with variable corneal compensation measurements in primary open-angle glaucoma

Cited by 7 publications

References 33 publications

Short-Term Reproducibility of Twenty-Four-Hour Intraocular Pressure Curves in Untreated Patients with Primary Open-Angle Glaucoma and Ocular Hypertension

Short-Term Reproducibility of Twenty-Four-Hour Intraocular Pressure Curves in Untreated Patients with Primary Open-Angle Glaucoma and Ocular Hypertension

Micropulse Laser Trabeculoplasty with 577 nm Wavelength at 1500 or 1000 mW for Primary Open-Angle Glaucoma: A Pilot Study

Comparison of Heidelberg retina tomography, optical coherence tomography and Humphrey visual field in early glaucoma diagnosis

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