Correlation Between Doppler Derived dP/dt and Left Ventricular Asynchrony in Patients with Dilated Cardiomyopathy: A Combined Study Using Strain Rate Imaging and Conventional Doppler Echocardiography

Abstract

Doppler-derived LV dP/dt is related to the degree of LV dyssynchrony rather than the conventional systolic function indices such as EF% in patients with severe heart failure. Noninvasive dP/dt assessment in addition to advanced imaging techniques can be used to define patients for cardiac resynchronization therapy (CRT).

Recognition of diastolic heart failure in the postoperative heart

“…Relaxation can be defined as the time period during which the myocardium loses its ability to generate force, shortens and returns to an unstressed length and force [17]. Peak negative change in the LV pressure over time (dp/dt) and the time constant of relaxation are accepted indices of the rate of relaxation, even though each of these factors has its own limitations [18]. In diastolic dysfunction relaxation abnormalities appear early and the inability of the left ventricle to fill in early diastole significantly affects the rapid filling phase resulting in a compensatory increase in filling with atrial contraction.…”