Correlation between Fatigue and Ability to Perform Activities of Daily Living in Myasthenia Gravis Patients

Permanasari, Adesti; Tinduh, Damayanti; Wardhani, Indrayuni Lukitra; Subadi, Imam; Sugianto, Paulus; Prawitri, Yudith Dian

doi:10.3889/oamjms.2022.8231

Cited by 3 publications

(2 citation statements)

References 21 publications

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“…The annual prevalence of MG is 72 cases per 1 000 000 population, with an incidence rate of roughly 0.25–2 cases per 1 000 000 people 4 . According to basic health study reports, the incidence of MG in Indonesia is estimated to be 1 case in 100 000 5 , 6 .…”

Section: Introductionmentioning

confidence: 99%

Correlation of fatigue on walking ability in myasthenia gravis patients: a cross-sectional study

Kartika,

Subadi,

Pawana

et al. 2023

Annals of Medicine &Amp; Surgery

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Introduction: Myasthenia gravis (MG) is a neuromuscular junction autoimmune disease characterised of intermittent muscle weakness that increases with activity and recovers with rest. Objective: Analysing the correlation of fatigue on walking ability in MG patients. Methods: This study used a cross-sectional design with consecutive sampling. Participants MG patients took in this trial. Data collection encompasses fatigue and walking ability, with fatigue being assessed using the fatigue severity scale (FSS) and walking ability being assessed using the 10-metre walking test. The 10-metre walking test assessment contains three components: comfortable walking speed (CWS), maximum walking speed (MWS), and natural cadence. The statistical analysis used in this study includes the Pearson correlation and Spearman rank tests with P<0.05. Results: The number of participants was 23 MG patients, and most of the participant was female (69.6%). The participant’s fatigue value was 5.46±1.13, including MGFA 1=5.32±1.15, MGFA 2A=5.5±1.11, and MGFA 2B=5.61±1.30. Meanwhile, the participant’s walking abilities included CWS of 1.10±0.11 m/s, MWS of 1.31±0.15 m/s, and natural cadence of 110.91±7.74 steps/min. No significant correlation of fatigue on walking ability including FSS vs. CWS (r=−0.141; P=0.520), FSS vs MWS (r=−0.169; P=0.442), and FSS vs. natural cadence (r=−0.050; P=0.822). Conclusion: There was no significant correlation between fatigue and walking ability in MG patients who had MGFA 1, MGFA 2A, and MGFA 2B.

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Section: Introductionmentioning

confidence: 99%

Correlation of fatigue on walking ability in myasthenia gravis patients: a cross-sectional study

Kartika,

Subadi,

Pawana

et al. 2023

Annals of Medicine &Amp; Surgery

Self Cite

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show abstract

“…Developmental delay defines as a condition when children fail to reach milestones that are caused by several domains, namely cognitive and performance, speech and language, gross and fine motor, psychological, sexual, and activities of daily living (ADL) (1)(2)(3). Although developmental delay is quite common in children, the detection of this disorder is still low (4,5).…”

Section: Introductionmentioning

confidence: 99%