Correlation between Global Longitudinal Strain and QRS Voltage on Electrocardiogram in Patients with Left Ventricular Hypertrophy

Abstract

These findings suggest that in pts with LVH, ECG should no longer be used only as a surrogate method for LVM estimation (structural changes only), but rather as an investigation complementary to imaging, incorporating information on overall LV remodeling (changes in structure and function).

Relationship between QRS measurements and left ventricular morphology and function in asymptomatic individuals

“…15 QRS amplitude has been clinically used in the diagnosis of LV hypertrophy (LVH) but proved to have limited sensitivity in predicting LV hypertrophy, irrespective of the imaging technique used. 12,44 This is supported by the independent relevance of the two variables in predicting cardiovascular mortality in normals and hypertensive patients. 45 In the absence of fixed slow depolarization, eg bundle branch block, the depolarization wave length is determined by myocardial thickness which is known to have mid-thickness fibrosis that itself adds to the slow conduction, as shown experimentally.…”

“…QRS amplitude has been clinically used in the diagnosis of LV hypertrophy (LVH) but proved to have limited sensitivity in predicting LV hypertrophy, irrespective of the imaging technique used . This is supported by the independent relevance of the two variables in predicting cardiovascular mortality in normals and hypertensive patients …”

“…The effect of LV size on QRS morphology is normally affected by gender, cavity geometry, and myocardial fiber orientation, as well as pathologically by ischemic heart disease, cardiomyopathies, myocardial fibrosis and pulmonary diseases . However, the diagnostic concordance between QRS morphology and echocardiographic or magnetic resonance estimation of LV mass and volume is limited and the direct association between changes in QRS amplitude and LV size remains controversial …”

Diagnostic utility of biomarkers of left ventricular stress in patients with aortic stenosis and preserved left ventricular ejection fraction

“…The Sokolow-Lyon index is a recognized prognostic factor for the presence of cardiac hypertrophy, regardless of etiology, including left ventricular hypertrophy (LVH) in patients with AS [16]. However, ECG criteria of LVH including the Sokolow-Lyon index do not correlate well with echocardiographic parameters of LVH [17, 18].…”

Atrioventricular depolarization differences identify coronary artery anomalies in Kawasaki disease

“…). This is more cost‐effective than assessing strain by echocardiogram, which can differentiate those KD patients with CAA from those without CAA (Beladan et al., ).…”