Expanding the theoretical knowledge of medical anthropology in the modern field of dental services is one of the main drivers of progress in the orthodontic field. The only way to successfully develop the relationship of these disciplines is to create and fill a database of normative data and search for correlations between various, both obviously related and, at first glance, completely unrelated structures of the human body. The purpose of the study was to determine the features of the relationship between the linear dimensions of molars with the cephalometric parameters of practically healthy men of the first mature age, residents of the western region of Ukraine. Cone-beam computed tomography was performed in 36 practically healthy men of the first mature age, residents of the western region of Ukraine (from Rivne, Volyn, Chernivtsi, Lviv, Ternopil, Khmelnytsky, Ivano-Frankivsk and Zakarpattia regions) followed by odontometry research and cephalometry. Statistical processing of the results was performed in the license package “Statistica 6.1” using non-parametric Spearman’s statistics. As a result of quantitative analysis of reliable and average strength of unreliable correlations of linear computed tomographic sizes of molars with cephalometric indicators and indices of practically healthy men of the western region of Ukraine it is established that the percentage, mainly direct, reliable and average strength of unreliable correlations of linear sizes of molars with cephalometric indices and with indicators of the cerebral or facial skull is almost no different. The largest number of reliable and medium-strength unreliable correlations of linear molars sizes with cranial indices was found with vestibular-lingual and mesio-distal tooth sizes (20.5% with upper molars and 25.0% with lower molars). The highest number of reliable and medium-strength unreliable correlations of linear molars sizes with facial skull indices was found for upper molars with tooth height, crowns and root length (10.8%) and vestibular-lingual and mesio-distal dimensions (12.8%), and for lower molars – only with vestibular-lingual and mesio-distal dimensions (19.4%). The obtained data testify to the prospects of the chosen scientific direction of research, which will further improve the work of physicians in various fields of medicine, including preventive.