Correlation between “malfunctioning events” and catheter-related infections in pediatric cancer patients bearing tunneled indwelling central venous catheter: results of a prospective observational study

Castagnola, Elio; Fratino, G.; Valera, Mariangela; Giacchino, M; Haupt, Riccardo; Molinari, Angelo Claudio

doi:10.1007/s00520-005-0802-y

Cited by 7 publications

(2 citation statements)

References 15 publications

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“…Although MD (71% of complications, 0.36 MD/1000 catheter‐days) was frequent in our series, the rate was within the range of previously published pediatric cohorts: Perdikaris et al reported 0.38 occlusions/1000 ICVC days, and other studies reported a mechanical complication rate of 0.45 per 1000 catheter‐days and 0.44 per 1000 catheter‐days . It must be emphasized that our MD definition was broader than those used by other authors.…”

Section: Discussionsupporting

confidence: 59%

Complications of indwelling central venous catheters in pediatric liver transplant recipients

Cousin

Wildhaber

Verolet

et al. 2016

Pediatric Transplantation

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In pLT recipients, the advantages of ICVCs need to be weighed against the risk of complications. This single-center retrospective study aimed to review ICVC complications in our cohort of pLT recipients. We performed chart reviews of pLT patients having undergone transplant between 01/2000 and 03/2014 and who underwent ICVC placement either before or after LT. We identified 100 ICVC in 85 patients. Overall observation time was 90 470 catheter-days. There was no difference in catheter lifespan between those inserted pre- or post-transplant; 46% of ICVC presented a complication. Most frequent complications were MD and infection. The infection rate was 0.09 per 1000 catheter-days, and MD rate was 0.36 per 1000 catheter-days. Patients having received technical variant grafts were more at risk of complications. To the best of our knowledge, this is the first study examining ICVC complications in pLT recipients. We conclude that ICVC have a high rate of MD. Children receiving technical variants may be more at risk of complications. By removing ICVC in a select number of patients at six months post-insertion, we might avoid as much as 60% of complications.

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Section: Discussionsupporting

confidence: 59%

Complications of indwelling central venous catheters in pediatric liver transplant recipients

Cousin

Wildhaber

Verolet

et al. 2016

Pediatric Transplantation

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“…Twelve studies 59,61,66,67,72,76,82,83,89,97,105,121 described the outcome of CVADassociated BSI without the clarity and rigor of benchmarked standards, which meant that their CVAD-associated BSI data were not included in the review. Two studies 30,116 provided combined "all-type" infection or mechanical failure outcomes, instead of providing separated local and systemic infection, occlusion, and dislodgement data.…”

Section: Study Qualitiesmentioning

confidence: 99%

Complications of Central Venous Access Devices: A Systematic Review

et al. 2015

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CONTEXT: The failure and complications of central venous access devices (CVADs) result in interrupted medical treatment, morbidity, and mortality for the patient. The resulting insertion of a new CVAD further contributes to risk and consumes extra resources.OBJECTIVE: To systematically review existing evidence of the incidence of CVAD failure and complications across CVAD types within pediatrics.DATA SOURCES: Central Register of Controlled Trials, PubMed, and Cumulative Index to Nursing and Allied Health databases were systematically searched up to January 2015.STUDY SELECTION: Included studies were of cohort design and examined the incidence of CVAD failure and complications across CVAD type in pediatrics within the last 10 years. CVAD failure was defined as CVAD loss of function before the completion of necessary treatment, and complications were defined as CVAD-associated bloodstream infection, CVAD local infection, dislodgement, occlusion, thrombosis, and breakage. CONCLUSIONS: CVAD failure and complications in pediatrics are a significant burden on the health care system internationally.

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Prophylaxis and Empirical Therapy of Infection in Cancer Patients

Viscoli¹,

Castagnola²

2010

Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases

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Correlation between “malfunctioning events” and catheter-related infections in pediatric cancer patients bearing tunneled indwelling central venous catheter: results of a prospective observational study

Abstract: Malfunctioning events followed by catheter related infections and catheter related infections followed by malfunctioning are both rare events in children with cancer.

Cited by 7 publications

References 15 publications

Complications of indwelling central venous catheters in pediatric liver transplant recipients

Complications of indwelling central venous catheters in pediatric liver transplant recipients

Complications of Central Venous Access Devices: A Systematic Review

Prophylaxis and Empirical Therapy of Infection in Cancer Patients

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