2022
DOI: 10.1002/jsp2.1183
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Correlation between motor behavior and age‐related intervertebral disc degeneration in cynomolgus monkeys

Abstract: Background The motor behavior in patients with lumbar intervertebral disc degeneration (IDD) and animal models should be changed due to pain. However, there does not seem to be a strong correlation between IDD and motor behavior. Therefore, it is necessary to understand the correlation between motor behavior and age‐related IDD. Methods Twenty‐one healthy male cynomolgus monkeys (Macaca fascicularis) distributed across the age range were included in this study. The experimental animals were divided into two gr… Show more

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Cited by 4 publications
(1 citation statement)
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“…The IVD tissue is an important load‐bearing structure of the spine, and its degenerative change is considered a major cause of neck pain and low back pain. 18 , 19 , 20 In previous studies, the degeneration of IVDs was considered an initiating factor for the degeneration of the spine, while the degeneration of FJs acted as an accompanied factor. 21 , 22 However, these studies only focused on the degeneration of lumbar spine.…”
Section: Discussionmentioning
confidence: 99%
“…The IVD tissue is an important load‐bearing structure of the spine, and its degenerative change is considered a major cause of neck pain and low back pain. 18 , 19 , 20 In previous studies, the degeneration of IVDs was considered an initiating factor for the degeneration of the spine, while the degeneration of FJs acted as an accompanied factor. 21 , 22 However, these studies only focused on the degeneration of lumbar spine.…”
Section: Discussionmentioning
confidence: 99%