Correlation between MTHFR Genotype Polymorphisms and Different Types of Migraine Headache in Iranian Patients: A Case Control Study

Abstract

Background: Migraine affects about 16% of the worldwide population. The pathogenesis of the disease consists of a combination of genetic and environmental factors. Given that, according to different polymorphism studies, ethnicity has a role in the gene diversity of migraine, this study was designed to determine the role of MTHFR C677T gene polymorphism in people from Tehran, Iran, who suffer from migraine headaches.