Correlation between myocardial deformation on three‐dimensional speckle tracking echocardiography and cardiopulmonary exercise testing

Abstract

Left ventricular early diastolic function is a modest independent predictor of aerobic exercise capacity. The 25%Untwist value is a good indicator of cardiac diastolic function.

Clinical Utility of Three-Dimensional Speckle-Tracking Echocardiography in Heart Failure

“…Patients with HF usually present with exercise intolerance and the gold standard for assessing clinical cardiopulmonary function is cardiopulmonary exercise testing (CPET) [ 66 ]. Combined with 3D-STE and CPET data from 156 subjects with different levels of cardiac function, Li et al found that the amount of 25% duration untwisting (25% untwist) was positively correlated with peak oxygen uptake (r = 0.41, p < 0.001) and negatively correlated with the CO 2 equivalent slope (r = −0.49, p < 0.001).…”

“…A total of 25% untwist value was a good indicator of LV early diastolic dysfunction, which is an independent predictor for examining aerobic exercise capacity. Cardiac function of HF patients with dyskinesia can be evaluated as an aid by revealing the relationship between cardiac diastolic function at rest and CPET [ 66 ].…”

Use of speckle tracking to assess heart failure with preserved ejection fraction

“…Other studies have compared STE on patients with HFpEF at rest and during exercise to evaluate prognostic parameters associated with increased risk of hospitalizations. In addition, exercise stress STE may provide an improved assessment of patients with HFpEF and direct treatment options to reduce symptom burden [77–79].…”

Three‐dimensional speckle‐tracking echocardiography for evaluating myocardial motion in patients with cardiorenal syndrome

“…Assessment of left ventricular function by three‐dimensional speckle tracking can be comparable to cardiac nuclear magnetic resonance . It was found that 25% untwist was related to oxygen uptake, which can be used as an independent predictor of aerobic exercise ability and a good indicator of cardiac diastolic function in patients with HF . 3D‐STE can also detect early left ventricular dysfunction caused by hypertrophic cardiomyopathy, essential hypertension, type 2 diabetes mellitus, and chemotherapy drugs .…”

“…35 It was found that 25% untwist was related to oxygen uptake, which can be used as an F I G U R E 4 Radial strain curves of left ventricular apical segments, obtained by three-dimensional speckle-tracking echocardiography (3D-STE) on short axis view in a patient with cardio-renal syndrome independent predictor of aerobic exercise ability and a good indicator of cardiac diastolic function in patients with HF. 36 3D-STE can also detect early left ventricular dysfunction caused by hypertrophic cardiomyopathy, 37 essential hypertension, 38 type 2 diabetes mellitus, 39 and chemotherapy drugs. 40 In addition to evaluating LV myocardial motion, 3D-STE can also evaluate the left atrium, 41 right atrium, 42…”