2021
DOI: 10.1007/s10815-021-02177-2
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Correlation between SNPs of PIK3CA, ERBB2 3′UTR, and their interactions with environmental factors and the risk of epithelial ovarian cancer

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Cited by 2 publications
(2 citation statements)
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“…Although the CHEK2 mutations were not confirmed as significant regarding the risk of ovarian cancer, other studies indicated that CHEK2 SNP rs17507066 had a significant association with the risk of HGSOC [20]. In a group of 587 studied patients with epithelial ovarian cancer, SNPs at PIK3CA rs9838117 and ERBB2 rs1058808 loci associated with cancer cell signaling were found to be correlated with the risk of cancer [29]. In the panel of genes related to ovarian cancer relapse, SNP analysis indicated that the male-specific lethal-1 homolog (MSL1) SNP rs7211770 was associated with a decreased risk of HGSOC (OR 0.81).…”
Section: Gene Polymorphismsmentioning
confidence: 91%
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“…Although the CHEK2 mutations were not confirmed as significant regarding the risk of ovarian cancer, other studies indicated that CHEK2 SNP rs17507066 had a significant association with the risk of HGSOC [20]. In a group of 587 studied patients with epithelial ovarian cancer, SNPs at PIK3CA rs9838117 and ERBB2 rs1058808 loci associated with cancer cell signaling were found to be correlated with the risk of cancer [29]. In the panel of genes related to ovarian cancer relapse, SNP analysis indicated that the male-specific lethal-1 homolog (MSL1) SNP rs7211770 was associated with a decreased risk of HGSOC (OR 0.81).…”
Section: Gene Polymorphismsmentioning
confidence: 91%
“…The changes in gut microbiota following antibiotic therapy included the increase in Bacteroidales species, which are negatively correlated with cancer, accompanied by the reduction or elimination of cancer-associated Prevotella. It seems that Bacteroidales in the fecal microbiota might prevent the recolonization of cancer-associated Prevotella and further inhibit HGSOC development [29].…”
Section: Bacterial Microbiomementioning
confidence: 99%