Correlation between spread through air spaces (STAS) and other clinicopathological parameters in lung cancer

Moreno, Juan Carlos Alvarez; Aljamal, Abed Alhalim; Bahmad, Hisham F.; Febres‐Aldana, Christopher A.; Rassaei, Negar; Recine, Monica; Poppiti, Robert

doi:10.1016/j.prp.2021.153376

Cited by 10 publications

(13 citation statements)

References 26 publications

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“…The incidence of STAS in our study was 71.2%, which was higher compared with the incidence observed by other authors (27.9%, 7 46%, 8 50.6%, 11 26.8% 12 and 32.4% 13 ). In contrast, Toyokawa et al .…”

Section: Discussioncontrasting

confidence: 76%

“… 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 The presence of STAS was associated with higher tumor stage, nodal involvement, micropapillary and solid growth patterns, absence of lepidic component, lymphovascular and perineural invasion and moderate/poorly differentiated tumors. 7 , 8 , 9 , 10 , 11 , 12 , 13 In addition, a high density of tumor-associated macrophage infiltration was related with an increased STAS rate. 15 In terms of molecular alteration, the conclusions of recent studies are controversial.…”

Section: Introductionmentioning

confidence: 94%

“…The incidence of STAS in lung adenocarcinoma ranges from 15% to 73% in related literature. 7 , 8 , 9 , 10 , 11 , 12 , 13 Since 2015, a large variety of studies have described the association of STAS and clinicopathologic features. 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 The presence of STAS was associated with higher tumor stage, nodal involvement, micropapillary and solid growth patterns, absence of lepidic component, lymphovascular and perineural invasion and moderate/poorly differentiated tumors.…”

Section: Introductionmentioning

confidence: 99%

“… 7 , 8 , 9 , 10 , 11 , 12 , 13 Since 2015, a large variety of studies have described the association of STAS and clinicopathologic features. 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 The presence of STAS was associated with higher tumor stage, nodal involvement, micropapillary and solid growth patterns, absence of lepidic component, lymphovascular and perineural invasion and moderate/poorly differentiated tumors. 7 , 8 , 9 , 10 , 11 , 12 , 13 In addition, a high density of tumor-associated macrophage infiltration was related with an increased STAS rate.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Retrospective analysis of the prognostic implications of tumor spread through air spaces in lung adenocarcinoma patients treated with surgery

Gutiérrez-Sainz

López-Muñoz²,

Cruz-Castellanos³

et al. 2022

ESMO Open

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Section: Discussioncontrasting

confidence: 76%

Section: Introductionmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Retrospective analysis of the prognostic implications of tumor spread through air spaces in lung adenocarcinoma patients treated with surgery

Gutiérrez-Sainz

López-Muñoz²,

Cruz-Castellanos³

et al. 2022

ESMO Open

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“…Its incidence rate and mortality rate are relatively high. Lung adenocarcinoma is a common form of NSCLC, and its incidence rate is about half of what mentioned in [ 2 ]. Previous researchers mainly focused on the malignant cells of cancer.…”

Section: Introductionmentioning

confidence: 99%

Study on the Relationship between Lung Cancer Stromal Cells and Air Cavity Diffusion Based on an Image Acquisition System

Bai

Wang

Sun

et al. 2022

Contrast Media & Molecular Imaging

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Objective. The study aimed to investigate the role of tumor stromal cells in the pathogenesis of STAS, the relationship between air diffusion (STAS) and tumor stromal cells (TSCs) was studied, and the prognostic significance of TSC and STAS in patients with lung adenocarcinoma was evaluated. Methods. A total of 150 patients with lung cancer diagnosed in the Affiliated Hospital of Jiangsu Province were selected. From the perspective of pathology, medical information technology was used to assist the diagnosis. The data of multiple magnetic resonance images were analyzed by three-dimensional space convolution (CNN), fuzzy neural network (FNN), transfinite learning machine (ELM), and binarization. Result. After data fusion, the specificity and sensitivity of multiple magnetic resonance (MRI) data are significantly higher than those of single MRI data, and the more fusion times, the better the sensitivity and specificity. With the increase in the number of information and data fusion, the proportion of the significant effect and the comprehensive effective rate of patients are on the rise. Multiple MRI data fusion examination and analysis under medical information technology can improve the cure rate of patients, and the 1-year survival rate and the 3-year survival rate of patients have also gradually improved. Conclusion. The MRI data fusion diagnosis method under the application of information technology can improve the sensitivity and specificity of the diagnosis results and comprehensively improve the clinical cure rate and the survival rate at different times of prognosis. In the context of the current big data information age, this multifeature fusion analysis technology is playing a more and more important role in medical treatment. The application of this method and technology not only improves the quality of life of patients but also processes multiple types of data at one time only by using the proposed medical assistant diagnosis model, which can save the diagnosis time to a certain extent. It has effectively realized the medical management and medical service quality and has important promotion significance.

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Spread Through Air Spaces (STAS) in Surgically Resected Lung Adenocarcinoma Prognosis

et al. 2023

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Correlation between spread through air spaces (STAS) and other clinicopathological parameters in lung cancer

Cited by 10 publications

References 26 publications

Retrospective analysis of the prognostic implications of tumor spread through air spaces in lung adenocarcinoma patients treated with surgery

Retrospective analysis of the prognostic implications of tumor spread through air spaces in lung adenocarcinoma patients treated with surgery

Study on the Relationship between Lung Cancer Stromal Cells and Air Cavity Diffusion Based on an Image Acquisition System

Spread Through Air Spaces (STAS) in Surgically Resected Lung Adenocarcinoma Prognosis

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