Correlation between the patients with Hepatitis C Virus and their Health-Related Quality of Life

Abstract

Background: Hepatitis C virus (HCV) infection is a global health problem and a major cause of morbidity and mortality. The current study aimed to assess the correlation between the patients with the hepatitis C virus and their health-related quality of life. Descriptive design was used. Setting: Carried out at liver virology outpatient. Subject: A convenient sample of two hundred adult patients with HCV newly received Sofosbuvir and Daclatasvir. Tools: Interview questioner and medical data sheet and Short-Form health survey (SF-36) questionnaire. Results: An improvement in the total quality of life this appear through 51.0% of hepatitis patients were poor in quality of life before treatment with Sofosbuvir and Daclatasvir medication while (62.0%) of them become excellent in quality of life after 3 months from treatment with highly statistically significant differences. Also, there was a fair negative association between the duration of disease of the studied patients with their total quality of life measured by shortform of health before administration of treatment with Sofosbuvir and Daclatasvir. Conclusion: The study concluded that the administration of Sofosbuvir and Daclatasvir for patients had positive effect on their quality of life especially for newly diagnosed patients. Recommendation: The study recommended that early screening for hepatitis C to begin early suitable treatment.

Investigating the Health-related Quality of Life in Hepatitis C Patients with Liver Cirrhosis Using Oral Antivirals, Before and after the Treatment

“…In the current study, the mean age of the hepatitis C patients with liver cirrhosis was 47.23 years, most of them were male, married, and had a high school diploma. The results are similar to those of the studies of Huang et al (2018) [27] and Abd ElHamied et al (2020) [28]. Also, in the systematic study by Peng et al (2019) [29], most of the patients with liver cirrhosis were in their 50s and male [29].…”

“…Therefore, the health-related quality of life is an important consequence to determine treatment and prognosis in these patients [22]. Since the ultimate goal in managing the patients with liver cirrhosis is not simply to increase life, but the main goal is to improve and maintain a relatively good quality of life [24], nurses should take measures to improve the quality of life in the patients with hepatitis C infection through teaching lifestyle changes, increasing knowledge, modifying behavior, reducing fatigue, and increasing the functional ability [28]. Despite the progress in the field of hepatitis C diagnosis, treatment, and care provision, the best way to eradicate the disease is to teach prevention methods and increase disease detection in the community, in which community health nurses can play an effective role [25].…”