Correlation between urea inclusion compounds and conformational structure of unsaturated C18 fatty acid methyl esters

Strocchi, A.; Bonaga, Giorgio

doi:10.1016/0009-3084(75)90033-x

Cited by 41 publications

(11 citation statements)

References 8 publications

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“…However, the simplest and most efficient technique for obtaining PUFA concentrates in the form of free fatty acids is urea complexation. This is a well-established technique for elimination of saturated and monounsaturated fatty acids (Gamez et al, 2003;Hermann, 1953;Iverson & Weik, 1967;Lucy & Jer, 2001;Strocchi, 1975;Tor & Yi, 2001). Initially the triacylglycerol (TAG) of the oil are split into their constituent fatty acids by alkaline hydrolysis using alcoholic 0260-8774/$ -see front matter Ó 2005 Elsevier Ltd. All rights reserved.…”

Section: Introductionmentioning

confidence: 97%

Concentration of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) of tuna oil by urea complexation: optimization of process parameters

Liu

Zhang

Hong

et al. 2006

Journal of Food Engineering

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Section: Introductionmentioning

confidence: 97%

Concentration of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) of tuna oil by urea complexation: optimization of process parameters

Liu

Zhang

Hong

et al. 2006

Journal of Food Engineering

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“…PUFA have been reported for their ability to lower serum triacylglycerol and cholesterol levels, to increase membrane fluidity and to eicosanoids to reduce thrombosis [4]. Urea complexation is the simplest and most efficient technique for obtaining PUFA concentrates in the form of free fatty acids and it is a well-established technique for the elimination of saturated and monounsaturated fatty acids [5]. With the growing public awareness of the nutritional benefits of consuming PUFA concentrates, the market for these products is expected to grow in the future.…”

Section: Introductionmentioning

confidence: 99%

Isolation of Linoleic Acid from Sambucus williamsii Seed Oil Extracted by High Pressure Fluid and Its Antioxidant, Antiglycemic, Hypolipidemic Activities

Chen

et al. 2015

International Journal of Food Engineering

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Linoleic acid was isolated effectively from Sambucus williamsii (SW) seed oil which was extracted by high-pressure fluid and its biological activities were investigated. Linoleic acid was isolated from the oil by urea inclusion, the yield was 65.81% and the purity was 92.12%. 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay was used to determine the antioxidant activity of linoleic acid. IC 50 of DPPH radical scavenging activity of linoleic acid was 61.92 mg/mL. The antiglycemic activity of linoleic acid was evaluated by determining its inhibitory effect on α-glucosidase. The results showed that α-glucosidase was inhibited to a certain extent by linoleic acid (1.56-25 mg/mL). In addition, the hypolipidemic activity of linoleic acid was investigated in vivo using hyperlipidemia mice models fed with the linoleic acid at doses of 1, 2, 4 g/kg BW (body weight). The results showed that serum lipid levels were highly significantly (p < 0.01) improved, which indicated the hypolipidemic activity of linoleic acid. The linoleic acid extracted from SW seed oil was proved to possess good antioxidant, antiglycemic and hypolipidemic activity in human diets, which may have industrial use.

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“…This is a well-established technique for the elimination of saturated and monounsaturated fatty acids [6,7]. Initially the triacylglycerols (TAG) of the oil are split into their constituent fatty acids by alkaline hydrolysis using alcoholic KOH or NaOH and these FFA are then mixed with an ethanol solution of urea for complex formation.…”

Section: Introductionmentioning

confidence: 99%

Optimizing Conditions for the Purification of Linoleic Acid from Sunflower Oil by Urea Complex Fractionation

Ding

Wang

et al. 2008

J Americ Oil Chem Soc

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The separation and purification of linoleic acid (LA) from sunflower seed oil by urea complex fractionation was studied. Crystallization reaction conditions of urea inclusion were optimized using the response surface method, and the optimal model was developed. Using the linear weighting method of the fitting model for optimization, the optimal balance between the purity and the recovery of LA was obtained. Under optimal conditions, the purity of LA was 87.8%, and the recovery was 83.4% at a urea-to-fatty acids ratio (w/w) of 0.94, 95% ethanol-tourea (v/w) of 5.00, a crystallization temperature of 18.0°C, and a crystallization time of 5.0 h. Verification results revealed that the predicted values from these models were reasonably close to the experimentally observed values.

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Correlation between urea inclusion compounds and conformational structure of unsaturated C18 fatty acid methyl esters

Cited by 41 publications

References 8 publications

Concentration of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) of tuna oil by urea complexation: optimization of process parameters

Concentration of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) of tuna oil by urea complexation: optimization of process parameters

Isolation of Linoleic Acid from Sambucus williamsii Seed Oil Extracted by High Pressure Fluid and Its Antioxidant, Antiglycemic, Hypolipidemic Activities

Optimizing Conditions for the Purification of Linoleic Acid from Sunflower Oil by Urea Complex Fractionation

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