Correlation of antioxidant activity and phytochemical profile in native plants

Abstract

Purpose -The purpose of this paper is to study the structure-activity correlation of four medicinal plants -Ocimum basilicum L., Piper betle L., Grewia asiatica L., Lantana camara L. in crude methanolic extract. These plants have been used in Ayurvedic preparation as alternative medicine. The contents of phenolic compounds (flavonoids, anthocyanin) and antioxidant capacities were evaluated. Design/methodology/approach -Folin-Ciocalteu method was used for the analysis of the phenolic compounds. Total flavonoids were also evaluated. DPPH, ABTS þ, FRAP and H 2 O 2 assays were used to evaluate antioxidant activity. Most of the assays were determined spectrometrically. Findings -O. basilicum L. had the highest of total phenolics content (305.11 mg GAE/g), highest content of anthocyanins (15.427 mg/Kg) and total flavonoids (9.692 QE mg/g). The DPPH, ABTS þ, FRAP and H 2 O 2 assay indicated that these plants possessed considerable antioxidant activities. Originality/value -The results also showed that O. basilicum and L. camara from red colored cultivars possessed high contents of phenolic compounds. FRAP assay showed AOA in the following sequence -Lantana camara . Ocimum basilicum . Piper betle . Grewia asiatica. Since L. camara showed highest antioxidant capacity thus it can be a potential resource for commercial antioxidant.

Phytochemical analysis and antioxidant activities of Lantana camara and Lantana montevidensis extracts

“…Previously it was reported that the methanolic extract of L. camara's flowers showed to be potentially effective in reducing iron, worth 29.90 mg of gallic acid/g of extract (Srivastava et al, 2012). Bangou et al (2012) reported that the reduction potential of the methanolic extract of L. camara's leaves was 8.17 mM ascorbic acid/g of extract, which is close to that observed for ethanol extract in this work.…”

Anticancer and anti-inflammatory perspectives of Pakistan’s indigenous berry Grewia asiatica Linn (Phalsa)

“…G. asiatica has been cited as a good source of phenolic acids, flavonoids and a small amount of tannins. However, more promising results have been delivered from the present study compared with earlier studies where G. asiatica methanolic extracts were found to deliver 144 mg GAE/g total phenolics, 4.61 mg QE/g total flavonoids and 4.9 mg/kg anthocyanins [33,34].…”

Bioactive Compounds, Vitamins and Minerals Composition of Freeze-dried Grewia asiatica L. (Phalsa) Pulp and Seed Powder

“…The obtained amount of anthocyanins in LPP was more as compared to fresh phalsa fruit, which attributed to rise in the dry matter content owing to the evaporation of water. Crude methanolic extracts of this fruit showed total phenols 144.11 mg GAE/g and total anthocyanin 4.88 mg/kg Srivastava et al (2012). Kaur and Kapoor (2005) also obtained moderate amounts of total phenols i.e., 55-87 mg/100g in phalsa.…”