Correlation of antioxidative properties and vaso-relaxation effects of major active constituents of traditional Chinese medicines

Zhang, Meng; Chen, Shilin; Seto, Sai Wang; Kwan, Yiu Wa; Chan, Shun‐Wan

doi:10.1080/13880200902753064

Cited by 8 publications

(1 citation statement)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In cardiovascular medicine screening, Zhang et al established the isolatedperfused mouse heart model according to Langendorff's for screening injected TCMs by monitoring cardiac function and coronary flow in vitro [20]. Zhang et al demonstrated that bioactive compounds isolated from TCMs possess unique "dual effects" that are beneficial in treating hypertension in rats' thoracic aortas [21]. The multitude of uncertain factors involved in this model affect the accuracy of the results and limit its application in the screening of TCMs [22].…”

Section: Introductionmentioning

confidence: 99%

Progress on the Screening and Analysis of Bioactive Compounds in Traditional Chinese Medicines by Biological Fingerprinting Analysis

Kong²,

Zou³

et al. 2010

CCHTS

View full text Add to dashboard Cite

Traditional Chinese medicines (TCMs), a key branch of natural medicines, play an important role in treatment of diseases because of their reliable clinical performance. Identification of their active compounds constitutes a bottleneck in the development of TCMs. Screening and analysis of active compounds is a challenge in TCMs research. This review summarizes recent progress in the development of biological fingerprinting strategies for screening and analyzing of bioactive compounds in TCMs using molecular recognition, metabolism and omics tools.The evaluated strategies including the following techniques: microdialysis/centrifugal ultrafiltration-HPLC, biochromatography, metabolic fingerprinting analysis, 2-dimensional biochromatography and omics fingerprinting analysis.

show abstract

Section: Introductionmentioning

confidence: 99%

Progress on the Screening and Analysis of Bioactive Compounds in Traditional Chinese Medicines by Biological Fingerprinting Analysis

Kong²,

Zou³

et al. 2010

CCHTS

View full text Add to dashboard Cite

show abstract

Geochemical characteristics and growth suitability assessment of Scutellaria baicalensis Georgi in the Earth’s critical zone of North China

Wei

et al. 2022

J. Mt. Sci.

View full text Add to dashboard Cite

Geochemical differentiation of soils has a series of consequences on plant and places pressure on the ecological environment. The quantitative evaluation of element migration in the Earth’s critical zone is a challenging task. In this study, two demonstration study areas of Scutellaria baicalensis Georgi were selected, and multiple chemical weathering indexes, chemical loss fraction, mass migration coefficients and biological enrichment coefficient method were used to assess the ecological and geochemical suitability. The results show that for the element of Fe, Zn, Se, Cu, Co, Ni, Mo and Ge, the degree of weathering and soil maturation, were greater in the rhyolitic tuff area than in the Plagioclase gneiss area. In both research sites, the heavy metal level of samples in Scutellaria baicalensis Georgi did not exceed the standard limits. The plagioclase gneiss region’s surface soil environment was more alkaline, and the content of soil organic matter was lower, resulting in a higher bioenrichment intensity of Ge, Co, Cu, and Se elements in Scutellaria baicalensis Georgi than in the rhyolite-tuff area. The elements of Cd, Nb, Mo, Pb and As are considerably enriched in the soil of the plagioclase gneiss area but lost by leaching in the soil of the rhyolite tuff area, which is connected to the interplay of elemental abundance and human impact in the parent materials. This study provides a good example of how to assess growth suitability of Chinese medicinal materials in the Earth’s critical zone. Electronic supplementary material Supplementary material (Appendix 1) is available in the online version of this article at 10.1007/s11629-021-7015-9.

show abstract

Chemical constituents of Ligusticum chuanxiong and their anti-inflammation and hepatoprotective activities

Yuan

Han

Feng

et al. 2020

Bioorganic Chemistry

View full text Add to dashboard Cite

Correlation of antioxidative properties and vaso-relaxation effects of major active constituents of traditional Chinese medicines

Cited by 8 publications

References 25 publications

Progress on the Screening and Analysis of Bioactive Compounds in Traditional Chinese Medicines by Biological Fingerprinting Analysis

Progress on the Screening and Analysis of Bioactive Compounds in Traditional Chinese Medicines by Biological Fingerprinting Analysis

Geochemical characteristics and growth suitability assessment of Scutellaria baicalensis Georgi in the Earth’s critical zone of North China

Chemical constituents of Ligusticum chuanxiong and their anti-inflammation and hepatoprotective activities

Contact Info

Product

Resources

About