Correlation of Cytologic and Histologic Findings in Fibrosing Thyroiditis

Blumenfeld, Walter

doi:10.1159/000333532

Cited by 7 publications

(4 citation statements)

References 10 publications

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“…14 In another case, FNA of RT was suspicious for a neoplasm due to atypical smear pattern with round cellular aggregates, which exhibited cell crowding, coarse cytoplasmic granularity, and prominent intranuclear inclusions. 15 Histologic examination of the excised specimen in this case showed RT. Although the authors concluded that the atypical cellular aggregates were due to the distortion of the follicular epithelium, a papillary neoplasm should be included in the differential diagnoses, since occasional cases of papillary thyroid cancer, especially the sclerosing variant, may accompanied by extensive fibrosis.…”

Section: Discussionmentioning

confidence: 64%

Fine‐needle aspiration of Riedel's disease: Report of a case and review of the literature

Harigopal

Sahoo

Recant

et al. 2004

Diagnostic Cytopathology

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The cytomorphological features of a case of Riedel's thyroiditis (Riedel's disease) in a 37-yr-old woman are reviewed. The patient presented with a diffusely enlarged thyroid gland with extension to carotid and jugular vessels bilaterally. A fine-needle aspiration of the right lobe of the thyroid demonstrated moderate cellularity with fragments of fibrous tissue with bland spindle-shaped cells and myofibroblasts. The patient subsequently underwent a bilateral subtotal thyroidectomy with removal of two-thirds of both lobes of the thyroid. A frozen section diagnosis of Riedel's disease was later confirmed on paraffin sections. Here we describe the cytological findings of a case of Riedel's disease and provide some helpful clues in distinguishing it from other forms of thyroiditis such as fibrosing variant of Hashimoto's thyroiditis, subacute thyroiditis, or granulomatous thyroiditis and from malignancy with which it can be confused both clinically and cytologically.

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Section: Discussionmentioning

confidence: 64%

Fine‐needle aspiration of Riedel's disease: Report of a case and review of the literature

Harigopal

Sahoo

Recant

et al. 2004

Diagnostic Cytopathology

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“…24 They are not found in needle aspirates of the diffuse sclerosing PTC variant or Riedel's thyroiditis, in which moderate-to-severe fibrous replacement of thyroid tissue occurs. 2,5,19 In a single Riedel's thyroiditis case that we saw, mostly single, atypical fibroblastic cells were present. It seems that as in fibroadenoma and phyllodes tumor of the breast, the fine needle is more prone to collect epithelial than stromal component.…”

Section: Discussionmentioning

confidence: 76%

Papillary Thyroid Carcinoma with Exuberant Nodular Fasciitis–like Stroma in a Fine Needle Aspirate

Us‐Krašovec

Golouh

1999

Acta Cytologica

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“…Indeed, in most cases, acellular or paucicellular, non-diagnostic smears are obtained [2, 3, 6, 7]. The fibrosclerotic process is the key feature of several thyroid diseases so that the clinician and the pathologist have to consider that many diagnostic pitfalls can occur in this field.…”

Section: Discussionmentioning

confidence: 99%

Fibrous Variant of Hashimoto’s Thyroiditis as a Diagnostic Pitfall in Thyroid Pathology

Iannaci¹,

Luise²,

Sapere³

et al. 2013

Case Reports in Endocrinology

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Fibrous variant of Hashimoto's thyroiditis is a rare condition occurring in about 10% cases, mainly middle age people. It is characterized by an extensive fibrous proliferation without extension into the surrounding structures. A 55-year-old female was referred to our department for an unexplained onset of cervical discomfort. She presented a voluminous goiter of hard consistence, dyspnea and dysphagia. Given the compressive symptoms and the non-diagnostic result of the biopsy, a total thyroidectomy was performed. Microscopically the thyroid parenchyma was characterized by broad bands of fibrosis with severe atrophy of thyroid follicles and lymphocytic inflammatory infiltrate distributed within and around the lobules. In view of the morphological and immunohistochemical findings, a diagnosis of HTFV was made. The fibrosclerotic process is the key feature of several thyroid diseases so that the clinician and the pathologist have to consider that many diagnostic pitfalls can occur in this field. The differential diagnosis between HTFV and RD is sometimes arduous due to the partial clinical and morphological overlapping and to the poor efficacy of conventional cytology as well as pre-surgical biopsy. Considering these features, histological examination is mostly mandatory.

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Correlation of Cytologic and Histologic Findings in Fibrosing Thyroiditis

Cited by 7 publications

References 10 publications

Fine‐needle aspiration of Riedel's disease: Report of a case and review of the literature

Fine‐needle aspiration of Riedel's disease: Report of a case and review of the literature

Papillary Thyroid Carcinoma with Exuberant Nodular Fasciitis–like Stroma in a Fine Needle Aspirate

Fibrous Variant of Hashimoto’s Thyroiditis as a Diagnostic Pitfall in Thyroid Pathology

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