2017
DOI: 10.1016/s0168-8278(17)30705-5
|View full text |Cite
|
Sign up to set email alerts
|

Correlation of efficacy and safety outcomes with regorafenib exposure in patients with hepatocellular carcinoma

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2020
2020
2020
2020

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
(1 citation statement)
references
References 0 publications
0
1
0
Order By: Relevance
“…An exploratory analysis showed that OS from the start of sorafenib therapy was 26.0 months in patients switched to regorafenib and 19.2 months in patients switched to placebo 39 . The safety of regorafenib in HCC was found to be consistent with its safety profile in other gastrointestinal malignancies, with no new safety concerns identified, including in subgroup analyses of Chinese patients, 40 and of patients with low, intermediate or high exposure to regorafenib 41 . HRQoL was assessed as a tertiary outcome using the Functional Assessment of Cancer Therapy (FACT) General and Hepatobiliary questionnaires and the European Quality of Life 5‐dimension and visual analogue scales, with no clinically meaningful differences found between patients treated with regorafenib and patients receiving placebo.…”
Section: Summary Of Data For Approved Second‐line Systemic Agentsmentioning
confidence: 78%
“…An exploratory analysis showed that OS from the start of sorafenib therapy was 26.0 months in patients switched to regorafenib and 19.2 months in patients switched to placebo 39 . The safety of regorafenib in HCC was found to be consistent with its safety profile in other gastrointestinal malignancies, with no new safety concerns identified, including in subgroup analyses of Chinese patients, 40 and of patients with low, intermediate or high exposure to regorafenib 41 . HRQoL was assessed as a tertiary outcome using the Functional Assessment of Cancer Therapy (FACT) General and Hepatobiliary questionnaires and the European Quality of Life 5‐dimension and visual analogue scales, with no clinically meaningful differences found between patients treated with regorafenib and patients receiving placebo.…”
Section: Summary Of Data For Approved Second‐line Systemic Agentsmentioning
confidence: 78%