Correlation of Expression of Estrogen Receptor, Progesterone Receptor and Human Epidermal Growth Factor Receptor-2 with Histopathological Grade in Cases of Carcinoma Breast

Abstract

Introduction: Breast carcinoma is the most common cancer among women in both developing and developed countries. It needs alarming attention because it causes high morbidity and mortality. There is a need to understand the initiation and progression of breast cancer on hormonal, cellular and molecular basis which forms the platform for designing of targeted therapy. This study was intended to find correlation between the expression of Estrogen receptor, Progesterone receptor and Human Epidermal Growth Factor Receptor-2 with histological grade in cases of carcinoma breast.