Correlation of mucocutaneous manifestations of HIV-infected patients in an ART center with CD4 counts

Lahoti, Sonal; Rao, Kavita; Umadevi, H S; Mishra, Lakshmi Chandra

doi:10.4103/ijdr.ijdr_352_16

Cited by 10 publications

(7 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The most common oral manifestation in males and females was found to be candidiasis (19.4%) with the average CD4 count of 191 ± 120.05 and the most common variant of candidiasis encountered was pseudomembranous type. These results are consistent with findings by various other investigators[815161718] who examined oral lesions and conditions associated with HIV-positive patients.…”

Section: Discussionsupporting

confidence: 93%

Correlation of CD4 counts with oral and systemic manifestations in HIV patients

Vohra

Jamatia

Subhada

et al. 2019

J Family Med Prim Care

View full text Add to dashboard Cite

Aim:Aim of the study was to correlate CD4 counts with oral and systemic manifestations in HIV patients.Materials and Methods:Study population comprised of newly diagnosed 100 confirmed seropositive patients, before starting any antiretroviral therapy, were included. The oral lesions were diagnosed based on clinical manifestation using international criteria and CD4 count was determined within maximum 1 week of oral examination. Oral and systemic manifestations of HIV-positive patients were recorded and correlated with CD4 counts.Results:It was found that decrease in CD4 count is associated with a wide range of oral and systemic manifestations which can be used as prognostic marker for immune suppression in AIDS patient.Conclusion:Correlation of CD4 count with oral and systemic manifestation in HIV patient demonstrate the role of oral physician in identification, diagnosis, and treatment of HIV-associated lesions, providing proper guidance to the patient and allowing for an early diagnosis and treatment of the disease, which is fundamental for a successful management of the life conditions of HIV infected patients.

show abstract

Section: Discussionsupporting

confidence: 93%

Correlation of CD4 counts with oral and systemic manifestations in HIV patients

Vohra

Jamatia

Subhada

et al. 2019

J Family Med Prim Care

View full text Add to dashboard Cite

show abstract

“…Human immunodeficiency virus (HIV) involves different tissues and organs, including the skin [ 1 ]. Not only are mucocutaneous lesions one of the most common manifestations in acquired immunodeficiency syndrome (AIDS), but also they act as sensitive and useful indicators of the immune status in the patients [ 1 – 4 ].Although these lesions can affect healthy individuals, they are usually more severe, atypical, widespread, and recalcitrant in HIV-infected patients [ 2 ]. Skin disorders are classified as primary and secondary in HIV-infected patients.…”

Section: Introductionmentioning

confidence: 99%

Mucocutaneous Manifestations in HIV-Infected Patients and Their Relationship to CD4 Lymphocyte Counts

et al. 2020

View full text Add to dashboard Cite

Background. More than 90% of human immunodeficiency virus- (HIV-) infected patients show at least one mucocutaneous manifestation during the course of their disease. The frequency, pattern, and associated factors of these complications vary among different populations. Objective. This study was planned to evaluate the frequency of cutaneous presentations in HIV-infected patients and their association with the count of CD4 cells. Methods. A cross-sectional study was conducted on eighty-four HIV-positive patients, who attended the Behavior Consultation Center of Arak University of Medical Sciences. All subjects had a complete physical examination by an expert dermatologist. Further diagnostic procedures were performed, if necessary. Counts of CD4 were determined using flow cytometry. Results. From 84 patients who enrolled in this study, 95.2% manifested at least one type of mucocutaneous lesions. The most common presentation was xerosis, followed by seborrheic dermatitis, herpes simplex, and oral candidiasis. Oral candidiasis and furuncle were significantly associated with decrease in CD4 cell counts. Conclusions. Cutaneous manifestations are common in HIV-positive patients, some of which (oral candidiasis and furuncle) could be applicable as useful clinical indicators to predict the immune status of the patients. Therefore, regular skin examinations are recommended as routine HIV-infected patients’ healthcare programs.

show abstract

“…Clinical manifestations of suspected HIV infection include weight loss of more 10% of previous body weight, fever for more than 1 month, chronic diarrhea, widespread lymphadenopathy, skin disorder (pruritic papular eruption), recurrent fungal infections, or recurrent viral infections. Early diagnosis of HIV infection and proper management can reduce morbidity, mortality and disease transmission (Lahoti et al, 2017).…”

Section: Discussionmentioning

confidence: 99%

“…Around 25% of HIV patients have VZV infection; therefore, this can be an indicator of adult patients (especially young adults) who are at risk of HIV. If reactivation occurs, it will become herpes zoster after several months of ARV therapy (Lahoti et al, 2017). Varicella incidents in HIV patients can increase morbidity, mortality and broad atypical lesions.…”

Section: Discussionmentioning

confidence: 99%

“…HIV and AIDS infections have become a national problem (Indonesia), and antiretroviral therapy (ARV) can reduce morbidity and mortality (Lahoti et al, 2017;Nasronudin, 2015). The incidence of VZV infection increases with worsening immune function; therefore, early diagnosis, proper management, and early detection of HIV infection may inhibit progression to AIDS (Jordaan, 2008).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Varicella-Infected Acquired Immunodeficiency Syndrome Patient with Secondary Infection

Razi

Rusli

Arfijanto

et al. 2017

Proceedings of the International Meeting on Regenerative Medicine

View full text Add to dashboard Cite

Human immunodeficiency virus and acquired immunodeficiency syndrome infections are major problems in Indonesia, and antiretroviral therapy can reduce morbidity and mortality. The incidence of Varicella-Zoster Virus infection increases with worsening immune function; therefore, early diagnosis, proper management, and early detection of Human immunodeficiency virus infection may inhibit acquired immunodeficiency syndrome progression. A woman aged 27 was admitted to the outpatient unit with blistered skin from one week before hospitalization. She was in a weak condition, and the skin appeared to have pus-filled bullae, partially crusted and visibly eroded with pus. She had a moderate fever, which worsened for one week to 39°C. She suffered from painful urination and bowel movements in the last one week when exposed to skin lesions around the genitals. She was diagnosed with Human immunodeficiency virus because of weight loss, chronic diarrhea, sprue, oris candidiasis, two-month fever, positive Human immunodeficiency virus rapid test; positive 3-method test and Cluster of Differentiation 4 cell count 17%. The Tzanck test showed the patient was positive with giant cells. Varicella diagnosis was clinically established, but positive Tzanck test, viral or Polymerase Chain Reaction cultures were not performed due to limited cost. According to the results of physical examination and laboratory examination, the patient was diagnosed with varicella with the complication of a secondary infection. Her condition improved during the treatment. Her prognosis improved, but she might later have herpes zoster risk.

show abstract

Correlation of mucocutaneous manifestations of HIV-infected patients in an ART center with CD4 counts

Cited by 10 publications

References 1 publication

Correlation of CD4 counts with oral and systemic manifestations in HIV patients

Correlation of CD4 counts with oral and systemic manifestations in HIV patients

Mucocutaneous Manifestations in HIV-Infected Patients and Their Relationship to CD4 Lymphocyte Counts

Varicella-Infected Acquired Immunodeficiency Syndrome Patient with Secondary Infection

Contact Info

Product

Resources

About