Correlation of Plasma Fibrinogen With Blood Pressure , Bmi, Lipid Profile and Glycemic Status in Type Ii D M

Harsoor, Suresh; Kinagi, Akshaya; Ananta, Ananta

doi:10.14260/jemds/2014/3963

Cited by 1 publication

(1 citation statement)

References 16 publications

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“…IL-6 was correlated linearly with BMI and WC in the study of Kluppelholz et al [26], Malenica et al [27], and Agrawal et al [28]. Similarly, Harsoor et al [29] and Kafle and Shrestha [20] showed a positive association of fibrinogen with BMI while Urbanavicius et al [30] depicted positive correlation of uric acid with BMI and WHR.…”

Section: Discussionmentioning

confidence: 93%

Study on the Association of Obesity Indices With Inflammatory Markers in Pre-Diabetes and Diabetes

Kumar

Shrestha

Prasad

et al. 2019

Asian J Pharm Clin Res

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Objective: In this study, the main objective was to evaluate the association of markers of obesity with the inflammatory markers in pre-diabetes and diabetes. Methods: This study recruited 300 participants (100 control group, 100 pre-diabetic group, and 100 diabetic group). The anthropometric variables such as body mass index (BMI), waist-hip ratio (WHR), and waist circumference (WC), and biochemical variables such as fasting blood glucose, glycated hemoglobin, uric acid, C-reactive protein (CRP), fibrinogen, interleukin-6 (IL-6), and adiponectin were analyzed in each participant by standard methods. Results: The present study documented significantly high values of BMI and WHR in patient (pre-diabetic and diabetic) groups compared to the control group. Similarly, the level of adiponectin decreased and that of uric acid, CRP, fibrinogen, and IL-6 increased significantly. Both BMI and WC were correlated significantly with inflammatory mediators in diabetic patients. The correlation with adiponectin was negative. In the pre-diabetic group, a significant correlation was observed only between WHR, adiponectin, and uric acid. Conclusion: This study supports the fact that obesity-induced systemic inflammation of low grade is significantly associated with pre-diabetes and diabetes, thereby keeping these individuals at high risk of future complications especially cardiovascular diseases.

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Section: Discussionmentioning

confidence: 93%