Correlation of plasma metabolites and comorbid illnesses with poor sleep quality in patients with coronary heart disease

The anti-fatigue and sleep-aiding effects vary significantly among different recipes containing Ganoderma lucidum extracts

“…This process results in an elevation of serum urea nitrogen levels [ 32 ], which can further promote muscular fatigue and reduce exercise endurance [ 33 ]. Lack of sleep also has a deleterious effect on metabolic function, leading to an increase in serum urea nitrogen content [ 34 ]. Furthermore, both high-intensity exercise and insomnia can trigger oxidative stress, damaging organs, cells and macromolecular substances [ [35] , [36] , [37] ].…”