Correlation of serum albumin and prognostic nutritional index with outcomes following pancreaticoduodenectomy

Rungsakulkij, Narongsak; Tangtawee, Pongsatorn; Suragul, Wikran; Muangkaew, Paramin; Mingphruedhi, Somkit; Aeesoa, Suraida

doi:10.12998/wjcc.v7.i1.28

Cited by 22 publications

(21 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The serum albumin concentration is affected by multiple factors, including nutritional status, liver failure, malignancy, surgical trauma, bacterial infection, inflammation, acute and chronic comorbidities (e.g., diabetes) and other conditions. 15 In the present study, all our patients experienced trauma. It is known that the stress response to injury is a factor that contributes to low preoperative serum levels.…”

Section: Discussionmentioning

confidence: 61%

“…17,25 Kamath A et al 20 reported that hypoalbuminaemia was independently associated with an increased risk of developing deep organ surgical-site infections, surgical-site infections, urinary traction infections, pneumonia and sepsis after revision total knee arthroplasty. Rungsakulkij N et al 15 reported that perioperative albumin was an important factor associated with serious complications following pancreaticoduodenectomy, include POP. This evidence was also supported by Munteanu A et al, 26 who reported that serum albumin levels, checked both before and after surgery, were of great value in helping predict a series of postoperative complications in gastric cancer surgery.…”

Section: Discussionmentioning

confidence: 99%

“…Preoperative malnutrition status has been identified as another potential risk factor and prognostic predictor for poor outcomes following hip fracture surgery. 13 Serum albumin level is the conventional indicator used as a biomarker of malnutrition, and patients are considered to have poor nutritional status when their serum albumin level is <35 g/L, 14 Several previous studies have indicated that preoperative serum albumin indicates susceptibility to the development of postoperative complications in patients with malignancies, including periampullary tumours, 15 colorectal cancer, 16 and lung cancer. 17 Likewise, in noncancer patients, the relationships between hypoalbuminaemia and poor postoperative outcomes have been studied.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

<p>Preoperative Serum Albumin Level As A Predictor Of Postoperative Pneumonia After Femoral Neck Fracture Surgery In A Geriatric Population</p>

Wang¹,

Li²,

Ji³

et al. 2019

CIA

View full text Add to dashboard Cite

Purpose: Femoral neck fracture usually occurs in the geriatric population. Postoperative pneumonia (POP) is known to be devastated, and it is the most frequent complication among patients receiving surgical treatment for femoral neck fractures. However, whether patients who have hypoalbuminaemia are susceptible to the development of POP is a serious concern, although it has not been investigated. We attempted to investigate the association between newly developed POP and hypoalbuminaemia and to identify whether hypoalbuminaemia is an independent risk factor for POP after femoral neck fracture in geriatric population. Patients and methods: We retrospectively reviewed the records from the first 30 days after surgery of patients who were ≥65 years of age and who had a femoral neck fracture treated with surgery between January 2018 and December 2018 at the Honghui Hospital, Xi'an Jiaotong University. Patients were divided into two groups based on whether they did or did not experience POP, and their clinical characteristics were compared. Binomial logistic regression was used to identify potential risk factors of POP by analysing demographic factors, preoperative comorbidities, laboratory results, and surgical factors. Results: A total of 720 patients were included in the analysis, and 54 patients experienced POP. The incidence of POP after surgical treatment for a femoral neck fracture in this geriatric population was 7.5%. In addition, patients with POP had significantly longer hospital stays than patients without POP. The binary logistic regression analysis revealed that preoperative hypoalbuminaemia [odds ratio =5.187, 95% confidence interval (CI): 2.561-10.506, P<0.0001], COPD (OR =3.819, 95% CI: 1.247-11.701, P=0.019), prior stroke (OR =3.107, 95% CI: 1.470-6.568, P=0.003) and the time from injury to surgery (OR =1.076, 95% CI: 1.034-1.119, P<0.0001) were predominant and independent risk factors associated with POP after femoral neck fracture in this geriatric population. Conclusion: The current study revealed that among a geriatric population admitted for femoral neck fracture surgery, preoperative hypoalbuminaemia was a predictor of POP, followed by COPD, prior stroke and the time from injury to surgery. Thus, patients who undergo femoral neck fracture surgery and have preoperative hypoalbuminaemia should receive additional monitoring and perioperative care.

show abstract

Section: Discussionmentioning

confidence: 61%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

<p>Preoperative Serum Albumin Level As A Predictor Of Postoperative Pneumonia After Femoral Neck Fracture Surgery In A Geriatric Population</p>

Wang¹,

Li²,

Ji³

et al. 2019

CIA

View full text Add to dashboard Cite

show abstract

“…The factors identified in previous studies as risk factors for SSI after PD include preoperative biliary drainage [2,7], pancreatic fistula [8], a high body mass index (BMI) [8], diabetes mellitus [7], blood transfusion [9], malnutrition, and a low serum albumin level [10][11][12]. As previous studies have revealed varying results, the primary aim of the present study was to identify the factors associated with SSI after PD, and the secondary aim was to identify adverse outcomes related to SSI after PD.…”

Section: Introductionmentioning

confidence: 99%

Predictors of surgical site infection after pancreaticoduodenectomy

et al. 2020

Self Cite

View full text Add to dashboard Cite

Background: Surgical site infection (SSI) is one of the most common complications after pancreaticoduodenectomy (PD). Thus, it is beneficial to preoperatively identify patients at high risk of developing SSI. The primary aim of the present study was to identify the factors associated with SSI after PD, and the secondary aim was to identify the adverse outcomes associated with the occurrence of SSI. Methods: A single-centre retrospective study was conducted. All 280 patients who underwent PD at our institution from January 2008 to December 2018 were enrolled. Demographic and perioperative data were reviewed, and the potential risk factors for developing SSI and the adverse outcomes related to SSI were analysed. Results: A total of 90 patients (32%) developed SSI. Fifty-one patients developed incisional SSI, and 39 developed organ/space SSI. Multivariate logistic analysis revealed that the significant risk factors for developing incisional SSI were preoperative biliary drainage (odds ratio, 3.04; 95% confidence interval, 1.36-6.79; p < 0.05) and postoperative pancreatic fistula (odds ratio, 2.78; 95% confidence interval, 1.43-5.38; p < 0.05), and the risk factors for developing organ/space SSI were preoperative cholangitis (odds ratio, 10.07; 95% confidence interval, 2.31-49.75; p < 0.05) and pancreatic fistula (odds ratio, 6.531; 95% confidence interval, 2.30-18.51; p < 0.05). Enterococcus spp., Escherichia coli and Klebsiella pneumoniae were the common bacterial pathogens that caused preoperative cholangitis as well as SSI after PD. The patients in the SSI group had a longer hospital stay and a higher rate of delayed gastric emptying than patients in the non-SSI group. Conclusions: The presence of postoperative pancreatic fistula was a significant risk factor for both incisional and organ/space SSI. Any efforts to reduce postoperative pancreatic fistula would decrease the incidence of incisional SSI as well as organ/space SSI after pancreaticoduodenectomy. Preoperative biliary drainage should be performed in selected patients to reduce the incidence of incisional SSI. Minimizing the occurrence of preoperative cholangitis would decrease the incidence of developing organ/space SSI.

show abstract

“…The preoperative serum albumin level is strongly associated with outcomes following various types of gastrointestinal surgery, including gastric, pancreatic, and colorectal surgery , as well as non‐gastrointestinal surgery . The association between serum albumin and IAI is controversial .…”

Section: Introductionmentioning

confidence: 99%

Preoperative serum albumin is associated with intra‐abdominal infection following major hepatectomy

Rungsakulkij

Vassanasiri

Tangtawee

et al. 2019

J Hepato Biliary Pancreat

Self Cite

View full text Add to dashboard Cite

Background Major hepatectomy is a complex surgical procedure with high morbidity. Intra-abdominal infection (IAI) is common following hepatectomy and affects treatment outcomes. This study was performed to investigate perioperative factors and determine whether the preoperative serum albumin level is associated with IAI following major hepatectomy. Methods From January 2008 to December 2018, 268 patients underwent major hepatectomy. We retrospectively analyzed demographic data and preoperative and perioperative variables. IAI was defined as organ/space surgical site infection. Risk factors for IAI were analyzed by logistic regression analysis. Results In total, 268 patients were evaluated. IAI was observed in 38 patients (14.6%). The mortality rate in the IAI group was 15.7%. Multivariate logistic analysis confirmed that the serum albumin level (odds ratio 0.91; 95% confidence interval 0.84-0.97; P = 0.03) and operative duration (odds ratio 1.50; 95% confidence interval 1.18-1.91; P < 0.01) were independent factors associated with IAI. A logistic model using the serum albumin level and operative duration to estimate the probability of IAI was analyzed. The area under the receiver operating characteristic curve for predicting IAI was 0.78. ConclusionThe serum albumin level and operative duration were independent factors predicting IAI following major hepatectomy.

show abstract

Correlation of serum albumin and prognostic nutritional index with outcomes following pancreaticoduodenectomy

Cited by 22 publications

References 43 publications

<p>Preoperative Serum Albumin Level As A Predictor Of Postoperative Pneumonia After Femoral Neck Fracture Surgery In A Geriatric Population</p>

<p>Preoperative Serum Albumin Level As A Predictor Of Postoperative Pneumonia After Femoral Neck Fracture Surgery In A Geriatric Population</p>

Predictors of surgical site infection after pancreaticoduodenectomy

Preoperative serum albumin is associated with intra‐abdominal infection following major hepatectomy

Contact Info

Product

Resources

About